Causal inference of sex hormone-binding globulin on venous thromboembolism: evidence from Mendelian randomisation

Causal inference of sex hormone-binding globulin on venous thromboembolism: evidence from Mendelian randomisation

Abstract Background Previous cohort studies have shown that exogenous sex hormone use, such as testosterone replacement therapy and oestrogen-containing contraceptives, can increase the risk of venous thromboembolism (VTE). However, the relationship between endogenous sex hormone levels and VTE rema...

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Bibliographic Details
Main Authors: Shuping Wang, Yongxiang Wang, Ming Bai, Yu Peng, Dan Zhou, Peng Lei, Binpeng Zhou, Piyi Zhang, Zheng Zhang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Thrombosis Journal
Subjects:
Sex hormone-binding globulin
Testosterone
Venous thromboembolism
Deep vein thrombosis
Pulmonary embolism
Mendelian randomisation
Online Access:https://doi.org/10.1186/s12959-023-00553-9

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