The protein-protein interaction between connective tissue growth factor and annexin A2 is relevant to pannus formation in rheumatoid arthritis

The protein-protein interaction between connective tissue growth factor and annexin A2 is relevant to pannus formation in rheumatoid arthritis

Abstract Background Connective tissue growth factor (CTGF)-induced angiogenesis is a crucial factor in rheumatoid arthritis (RA), but CTGF-interacting protein and related molecular mechanism of their interaction have not been fully elucidated. Methods CTGF-interacting proteins were identified throug...

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Bibliographic Details
Main Authors: Guoyu Yin, Chenglin Yang, Gan Wu, Xinxin Yu, Qingqing Tian, Daoxing Chen, Ben Cao, Lin Zhao, Nannan Xu, Shengwei Jin, Wei Zhang, Jianguang Wang
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis (RA)
Pannus formation
Annexin A2 (ANXA2)
Connective tissue growth factor (CTGF)
Online Access:https://doi.org/10.1186/s13075-021-02656-y

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