Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish.

Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish.

Interferon regulatory factor 8 (Irf8) is critical for mammalian macrophage development and innate immunity, but its role in teleost myelopoiesis remains incompletely understood. In particular, genetic tools to analyze the role of Irf8 in zebrafish macrophage development at larval and adult stages ar...

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Bibliographic Details
Main Authors: Celia E Shiau, Zoe Kaufman, Ana M Meireles, William S Talbot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4304715?pdf=render

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