Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton

The influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidi...

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Main Authors: I. V. Kovalyev, S. V. Gusakova, O. S. Melnik, M. B. Baskakov, L. V. Kapilevich, M. A. Medvedev, V. B. Studnitsky, O. I. Antonov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2009-08-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1885
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author I. V. Kovalyev
S. V. Gusakova
O. S. Melnik
M. B. Baskakov
L. V. Kapilevich
M. A. Medvedev
V. B. Studnitsky
O. I. Antonov
author_facet I. V. Kovalyev
S. V. Gusakova
O. S. Melnik
M. B. Baskakov
L. V. Kapilevich
M. A. Medvedev
V. B. Studnitsky
O. I. Antonov
author_sort I. V. Kovalyev
collection DOAJ
description The influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidirectional influence of hydrogen peroxide in the reduction of smooth muscles of rat aorta with the membrane depolarization hyperpotassium solution and action phenylephrine: phenylephrine decline in value and increase strength hyperpotassium contractures. We show that the cytoskeleton components involved in the mechanisms of action of hydrogen peroxide in the contractile reactions of smooth muscles of rat aorta caused by phenylephrine.
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spelling doaj.art-73b363f6ba4f4e8c890e93ea2d2e43842023-03-13T09:58:11ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842009-08-0184414610.20538/1682-0363-2009-4-41-461379Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeletonI. V. Kovalyev0S. V. Gusakova1O. S. Melnik2M. B. Baskakov3L. V. Kapilevich4M. A. Medvedev5V. B. Studnitsky6O. I. Antonov7Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe influence of of hydrogen peroxide on the contractile reactions of smooth muscle cells caused by hyperpotassium solution end phenylephrine in modulation a potassium conductance the membrane and the state of cytoskeleton elements has been investigated by the mechanographical method. It has multidirectional influence of hydrogen peroxide in the reduction of smooth muscles of rat aorta with the membrane depolarization hyperpotassium solution and action phenylephrine: phenylephrine decline in value and increase strength hyperpotassium contractures. We show that the cytoskeleton components involved in the mechanisms of action of hydrogen peroxide in the contractile reactions of smooth muscles of rat aorta caused by phenylephrine.https://bulletin.ssmu.ru/jour/article/view/1885гладкомышечные клеткицитоскелетактивные формы кислородаперекись водорода
spellingShingle I. V. Kovalyev
S. V. Gusakova
O. S. Melnik
M. B. Baskakov
L. V. Kapilevich
M. A. Medvedev
V. B. Studnitsky
O. I. Antonov
Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
Бюллетень сибирской медицины
гладкомышечные клетки
цитоскелет
активные формы кислорода
перекись водорода
title Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
title_full Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
title_fullStr Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
title_full_unstemmed Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
title_short Hydrogen peroxide influence on contractile activity smooth muscle cells: the role of cytoskeleton
title_sort hydrogen peroxide influence on contractile activity smooth muscle cells the role of cytoskeleton
topic гладкомышечные клетки
цитоскелет
активные формы кислорода
перекись водорода
url https://bulletin.ssmu.ru/jour/article/view/1885
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AT svgusakova hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
AT osmelnik hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
AT mbbaskakov hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
AT lvkapilevich hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
AT mamedvedev hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
AT vbstudnitsky hydrogenperoxideinfluenceoncontractileactivitysmoothmusclecellstheroleofcytoskeleton
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