Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

Brain aging is central to late-onset Alzheimer's disease (LOAD), although the mechanisms by which it occurs at protein or cellular levels are not fully understood. Alzheimer's disease is the most common proteopathy and is characterized by two unique pathologies: senile plaques and neurofib...

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Bibliographic Details
Main Authors:	Kevin A. Clayton, Alicia A. Van Enoo, Tsuneya Ikezu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-12-01
Series:	Frontiers in Neuroscience
Subjects:	Alzheimer's disease microglia neurodegeneration amyloid-beta peptide tau protein neuroinflammation
Online Access:	http://journal.frontiersin.org/article/10.3389/fnins.2017.00680/full

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