Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022
Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/1/12 |
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| author | Norosoa Harline Razanajatovo Tsiry Hasina Randriambolamanantsoa Joelinotahiana Hasina Rabarison Laurence Randrianasolo Miamina Fidy Ankasitrahana Arvé Ratsimbazafy Antso Hasina Raherinandrasana Helisoa Razafimanjato Vololoniaina Raharinosy Soa Fy Andriamandimby Jean-Michel Heraud Philippe Dussart Vincent Lacoste |
| author_facet | Norosoa Harline Razanajatovo Tsiry Hasina Randriambolamanantsoa Joelinotahiana Hasina Rabarison Laurence Randrianasolo Miamina Fidy Ankasitrahana Arvé Ratsimbazafy Antso Hasina Raherinandrasana Helisoa Razafimanjato Vololoniaina Raharinosy Soa Fy Andriamandimby Jean-Michel Heraud Philippe Dussart Vincent Lacoste |
| author_sort | Norosoa Harline Razanajatovo |
| collection | DOAJ |
| description | Three epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respiratory viruses (RVs) in Madagascar. We used two different specimen sources (SpS). First, 2987 nasopharyngeal (NP) specimens were randomly selected from symptomatic patients between March 2020 and May 2022 who tested negative for SARS-CoV-2 and were tested for 14 RVs by multiplex real-time PCR. Second, 6297 NP specimens were collected between March 2020 and May 2022 from patients visiting our sentinel sites of the influenza sentinel network. The samples were tested for influenza, respiratory syncytial virus (RSV), and SARS-CoV-2. From SpS-1, 19% (569/2987) of samples tested positive for at least one RV. Rhinovirus (6.3%, 187/2987) was the most frequently detected virus during the first two waves, whereas influenza predominated during the third. From SpS-2, influenza, SARS-CoV-2, and RSV accounted for 5.4%, 24.5%, and 39.4% of the detected viruses, respectively. During the study period, we observed three different RV circulation profiles. Certain viruses circulated sporadically, with increased activity in between waves of SARS-CoV-2. Other viruses continued to circulate regardless of the COVID-19 situation. Certain viruses were severely disrupted by the spread of SARS-CoV-2. Our findings underline the importance and necessity of maintaining an integrated disease surveillance system for the surveillance and monitoring of RVs of public health interest. |
| first_indexed | 2024-03-09T11:03:19Z |
| format | Article |
| id | doaj.art-73b8bdb7710547e188253178df3872ad |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T11:03:19Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-73b8bdb7710547e188253178df3872ad2023-12-01T01:06:06ZengMDPI AGViruses1999-49152022-12-011511210.3390/v15010012Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022Norosoa Harline Razanajatovo0Tsiry Hasina Randriambolamanantsoa1Joelinotahiana Hasina Rabarison2Laurence Randrianasolo3Miamina Fidy Ankasitrahana4Arvé Ratsimbazafy5Antso Hasina Raherinandrasana6Helisoa Razafimanjato7Vololoniaina Raharinosy8Soa Fy Andriamandimby9Jean-Michel Heraud10Philippe Dussart11Vincent Lacoste12National Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarEpidemiology and Clinical Research Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarDirection de la Veille Sanitaire, de la Surveillance Epidémiologique et Ripostes, Ministry of Public Health, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarVirology Department, Institut Pasteur de Dakar, Dakar 12900, SenegalNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarNational Influenza Center, Virology Unit, Institut Pasteur of Madagascar, Antananarivo 101, MadagascarThree epidemic waves of coronavirus disease-19 (COVID-19) occurred in Madagascar from March 2020 to May 2022, with a positivity rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 21% to 33%. Our study aimed to identify the impact of COVID-19 on the epidemiology of seasonal respiratory viruses (RVs) in Madagascar. We used two different specimen sources (SpS). First, 2987 nasopharyngeal (NP) specimens were randomly selected from symptomatic patients between March 2020 and May 2022 who tested negative for SARS-CoV-2 and were tested for 14 RVs by multiplex real-time PCR. Second, 6297 NP specimens were collected between March 2020 and May 2022 from patients visiting our sentinel sites of the influenza sentinel network. The samples were tested for influenza, respiratory syncytial virus (RSV), and SARS-CoV-2. From SpS-1, 19% (569/2987) of samples tested positive for at least one RV. Rhinovirus (6.3%, 187/2987) was the most frequently detected virus during the first two waves, whereas influenza predominated during the third. From SpS-2, influenza, SARS-CoV-2, and RSV accounted for 5.4%, 24.5%, and 39.4% of the detected viruses, respectively. During the study period, we observed three different RV circulation profiles. Certain viruses circulated sporadically, with increased activity in between waves of SARS-CoV-2. Other viruses continued to circulate regardless of the COVID-19 situation. Certain viruses were severely disrupted by the spread of SARS-CoV-2. Our findings underline the importance and necessity of maintaining an integrated disease surveillance system for the surveillance and monitoring of RVs of public health interest.https://www.mdpi.com/1999-4915/15/1/12virusesSARS-CoV-2epidemicsepidemiologyetiologydetection |
| spellingShingle | Norosoa Harline Razanajatovo Tsiry Hasina Randriambolamanantsoa Joelinotahiana Hasina Rabarison Laurence Randrianasolo Miamina Fidy Ankasitrahana Arvé Ratsimbazafy Antso Hasina Raherinandrasana Helisoa Razafimanjato Vololoniaina Raharinosy Soa Fy Andriamandimby Jean-Michel Heraud Philippe Dussart Vincent Lacoste Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 Viruses viruses SARS-CoV-2 epidemics epidemiology etiology detection |
| title | Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 |
| title_full | Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 |
| title_fullStr | Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 |
| title_full_unstemmed | Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 |
| title_short | Epidemiological Patterns of Seasonal Respiratory Viruses during the COVID-19 Pandemic in Madagascar, March 2020–May 2022 |
| title_sort | epidemiological patterns of seasonal respiratory viruses during the covid 19 pandemic in madagascar march 2020 may 2022 |
| topic | viruses SARS-CoV-2 epidemics epidemiology etiology detection |
| url | https://www.mdpi.com/1999-4915/15/1/12 |
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