Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study

<p>Abstract</p> <p>Background</p> <p>There are hardly any studies carried out in Pakistan on the usage of benzodiazepines at the level of community. This research was aimed to determine the frequency of benzodiazepine use, along with its associations with socio-demograp...

Full description

Bibliographic Details
Main Authors: Tharani Ambreen, Parpio Yasmin, Farooq Salima, Ahmer Syed, Iqbal Saleem P, Khan Rashid AM, Zaman Mohammad
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Substance Abuse Treatment, Prevention, and Policy
Online Access:http://www.substanceabusepolicy.com/content/6/1/19
_version_ 1818355396226580480
author Tharani Ambreen
Parpio Yasmin
Farooq Salima
Ahmer Syed
Iqbal Saleem P
Khan Rashid AM
Zaman Mohammad
author_facet Tharani Ambreen
Parpio Yasmin
Farooq Salima
Ahmer Syed
Iqbal Saleem P
Khan Rashid AM
Zaman Mohammad
author_sort Tharani Ambreen
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>There are hardly any studies carried out in Pakistan on the usage of benzodiazepines at the level of community. This research was aimed to determine the frequency of benzodiazepine use, along with its associations with socio-demographic and clinical characteristics among community dwelling adults, residing in two urban settlements of Karachi, Pakistan.</p> <p>Methods</p> <p>We performed a cross sectional study from August 2008 to December 2009, in 2 areas of Karachi, namely Garden and Sultanabad. We followed the systematic sampling strategy to randomly select the households, with an adult of either sex and of age 18 years or more. Data collection was carried out through interview, using a pre-tested questionnaire, with items on socio-demographic position, medical history and benzodiazepine use. Student's t-test and χ<sup>2 </sup>test was employed to determine the associations between socio-demographic and clinical characteristics, and their relationship with benzodiazepine use was determined using applied logistic regression.</p> <p>Results</p> <p>The overall percentage of benzodiazepine consumption was estimated to be 14%. There were significantly more benzodiazepine users in the peri-urban Sultanabad community to the urban community of Garden (p-value = 0.001). The mean age (± SD) for users was 51.3 (± 15.6) years compared to 37.1 (± 14.4) years among non-users. Bromazepam was the most widely used benzodiazepine (29%); followed by diazepam, with a median duration on primary use being 144 weeks (IQR = 48-240). The adjusted logistic regression model revealed that increasing age, location, female sex, unemployment and psychiatric consultation were associated with increased likelihood of benzodiazepine use.</p> <p>Conclusion</p> <p>We believe the unregulated over-the-counter sales of benzodiazepines and social conditions might be playing a role in this high consumption of benzodiazepines in the community.</p>
first_indexed 2024-12-13T19:40:39Z
format Article
id doaj.art-73b9f091568b4d86aebe9ca4660e3506
institution Directory Open Access Journal
issn 1747-597X
language English
last_indexed 2024-12-13T19:40:39Z
publishDate 2011-08-01
publisher BMC
record_format Article
series Substance Abuse Treatment, Prevention, and Policy
spelling doaj.art-73b9f091568b4d86aebe9ca4660e35062022-12-21T23:33:41ZengBMCSubstance Abuse Treatment, Prevention, and Policy1747-597X2011-08-01611910.1186/1747-597X-6-19Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional studyTharani AmbreenParpio YasminFarooq SalimaAhmer SyedIqbal Saleem PKhan Rashid AMZaman Mohammad<p>Abstract</p> <p>Background</p> <p>There are hardly any studies carried out in Pakistan on the usage of benzodiazepines at the level of community. This research was aimed to determine the frequency of benzodiazepine use, along with its associations with socio-demographic and clinical characteristics among community dwelling adults, residing in two urban settlements of Karachi, Pakistan.</p> <p>Methods</p> <p>We performed a cross sectional study from August 2008 to December 2009, in 2 areas of Karachi, namely Garden and Sultanabad. We followed the systematic sampling strategy to randomly select the households, with an adult of either sex and of age 18 years or more. Data collection was carried out through interview, using a pre-tested questionnaire, with items on socio-demographic position, medical history and benzodiazepine use. Student's t-test and χ<sup>2 </sup>test was employed to determine the associations between socio-demographic and clinical characteristics, and their relationship with benzodiazepine use was determined using applied logistic regression.</p> <p>Results</p> <p>The overall percentage of benzodiazepine consumption was estimated to be 14%. There were significantly more benzodiazepine users in the peri-urban Sultanabad community to the urban community of Garden (p-value = 0.001). The mean age (± SD) for users was 51.3 (± 15.6) years compared to 37.1 (± 14.4) years among non-users. Bromazepam was the most widely used benzodiazepine (29%); followed by diazepam, with a median duration on primary use being 144 weeks (IQR = 48-240). The adjusted logistic regression model revealed that increasing age, location, female sex, unemployment and psychiatric consultation were associated with increased likelihood of benzodiazepine use.</p> <p>Conclusion</p> <p>We believe the unregulated over-the-counter sales of benzodiazepines and social conditions might be playing a role in this high consumption of benzodiazepines in the community.</p>http://www.substanceabusepolicy.com/content/6/1/19
spellingShingle Tharani Ambreen
Parpio Yasmin
Farooq Salima
Ahmer Syed
Iqbal Saleem P
Khan Rashid AM
Zaman Mohammad
Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
Substance Abuse Treatment, Prevention, and Policy
title Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
title_full Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
title_fullStr Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
title_full_unstemmed Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
title_short Benzodiazepine use among adults residing in the urban settlements of Karachi, Pakistan: A cross sectional study
title_sort benzodiazepine use among adults residing in the urban settlements of karachi pakistan a cross sectional study
url http://www.substanceabusepolicy.com/content/6/1/19
work_keys_str_mv AT tharaniambreen benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT parpioyasmin benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT farooqsalima benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT ahmersyed benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT iqbalsaleemp benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT khanrashidam benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy
AT zamanmohammad benzodiazepineuseamongadultsresidingintheurbansettlementsofkarachipakistanacrosssectionalstudy