Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics

Metabolite profiling, antimalarial potentials of Schleichera oleosa using LC-MS and GC-MS: in vitro, molecular docking and molecular dynamics

PurposeTo explore the phytochemical composition of Schleichera oleosa bark and evaluate its potential antimalarial activity through in vitro and in silico analyses.MethodsThe bark of S. oleosa was subjected to Soxhlet extraction using petroleum ether, chloroform, and methanol. The quantitative analy...

Full description

Bibliographic Details
Main Authors: Peetha Vanaja, N. S. Hari Narayana Moorthy, Vivek Singh Rajpoot, Harshawardhan Rao, Rohit Kumar Goswami, Paranthaman Subash, Sulekha Khute, Kareti Srinivasa Rao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
antimalarial
in silico
in vitro
phytoconstituents
Schleichera oleosa
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1543939/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2025.1543939/full

Similar Items