Design, Construction and Immunogenicity Assessment of pEGFP-N1-KMP11-GP96 (Fusion) as a DNA Vaccine Candidate against Leishmania major Infection in BALB/c Mice

Design, Construction and Immunogenicity Assessment of pEGFP-N1-KMP11-GP96 (Fusion) as a DNA Vaccine Candidate against Leishmania major Infection in BALB/c Mice

Background: KMP-11 (Kinetoplastid membrane protein-Π) exists in all species of kinetoplastid family. It is fully conserved and the protein produced by this gene can induce a very high cellular immune response. We aimed to design a suitable construction for a Leishmania major DNA vaccine and evaluate...

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Bibliographic Details
Main Authors:	Abdolhossein DALIMI, Vahid NASIRI
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 2020-03-01
Series:	Iranian Journal of Parasitology
Subjects:	Leishmania major Fusion gene Vaccine
Online Access:	https://ijpa.tums.ac.ir/index.php/ijpa/article/view/2828

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