Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic

Background. After the declaration of the pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence a...

Full description

Bibliographic Details
Main Authors: Fabio Ferretti, Arianna Goracci, Pier Francesco Laurenzi, Rossella Centola, Irene Crecchi, Aldo De Luca, Janette Monzillo, Omar Guidi, Giusy Sinigaglia, Giacomo Gualtieri, Lore Lorenzi, Alessandro Cuomo, Simone Bolognesi, Valter Travagli, Anna Coluccia, Andrea Fagiolini, Andrea Pozza
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/10/1315
_version_ 1797474784448086016
author Fabio Ferretti
Arianna Goracci
Pier Francesco Laurenzi
Rossella Centola
Irene Crecchi
Aldo De Luca
Janette Monzillo
Omar Guidi
Giusy Sinigaglia
Giacomo Gualtieri
Lore Lorenzi
Alessandro Cuomo
Simone Bolognesi
Valter Travagli
Anna Coluccia
Andrea Fagiolini
Andrea Pozza
author_facet Fabio Ferretti
Arianna Goracci
Pier Francesco Laurenzi
Rossella Centola
Irene Crecchi
Aldo De Luca
Janette Monzillo
Omar Guidi
Giusy Sinigaglia
Giacomo Gualtieri
Lore Lorenzi
Alessandro Cuomo
Simone Bolognesi
Valter Travagli
Anna Coluccia
Andrea Fagiolini
Andrea Pozza
author_sort Fabio Ferretti
collection DOAJ
description Background. After the declaration of the pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence amongst individuals with mental illness during the COVID-19 pandemic. This brief report describes a preliminary naturalistic longitudinal study that explored whether the Big Five personality traits prospectively moderate the effects of medication beliefs on changes in adherence during the pandemic for a group of outpatients with psychosis or bipolar disorder. Methods. Thirteen outpatients undergoing routine face-to-face follow-up assessments during the pandemic were included (41 observations overall) and completed the Revised Italian Version of the Ten-Item Personality Inventory, the Beliefs about Medicines Questionnaire, the Morisky Medication Adherence Scale—8-item and the Beck Depression Inventory—II. Results. Participants had stronger concerns about their psychiatric medications rather than beliefs about their necessity, and adherence to medications was generally low. Participants who had more necessity beliefs than concerns had better adherence to medications. People scoring higher in Conscientiousness and Neuroticism traits and more concerned about the medication side effects had poorer adherence. Conclusions. These preliminary data suggest the importance of a careful assessment of the adherence to medications amongst people with psychosis/bipolar disorder during the pandemic. Interventions aimed to improve adherence might focus on patients’ medication beliefs and their Conscientiousness and Neuroticism personality traits.
first_indexed 2024-03-09T20:35:00Z
format Article
id doaj.art-73c10479002a4b11bd6b2ae186dbfc97
institution Directory Open Access Journal
issn 2076-3425
language English
last_indexed 2024-03-09T20:35:00Z
publishDate 2022-09-01
publisher MDPI AG
record_format Article
series Brain Sciences
spelling doaj.art-73c10479002a4b11bd6b2ae186dbfc972023-11-23T23:13:28ZengMDPI AGBrain Sciences2076-34252022-09-011210131510.3390/brainsci12101315Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the PandemicFabio Ferretti0Arianna Goracci1Pier Francesco Laurenzi2Rossella Centola3Irene Crecchi4Aldo De Luca5Janette Monzillo6Omar Guidi7Giusy Sinigaglia8Giacomo Gualtieri9Lore Lorenzi10Alessandro Cuomo11Simone Bolognesi12Valter Travagli13Anna Coluccia14Andrea Fagiolini15Andrea Pozza16Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, ItalyDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, ItalyDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, ItalyUOC Farmacia, AOU San Giovanni di Dio e Ruggi d’Aragona, 84131 Salerno, ItalyUOC Farmacia Ospedaliera, Azienda Ospedaliera Universitaria Senese, 53100 Siena, ItalyFarmacia, Istituto Nazionale Malattie Infettive “L. Spallanzani” IRCCS, 00149 Rome, ItalyScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, ItalyScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, ItalyScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, ItalyDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, ItalyDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, ItalyDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, ItalyDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, ItalyUOC Farmacia Ospedaliera, Azienda Ospedaliera Universitaria Senese, 53100 Siena, ItalyDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, ItalyDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, ItalyDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, ItalyBackground. After the declaration of the pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence amongst individuals with mental illness during the COVID-19 pandemic. This brief report describes a preliminary naturalistic longitudinal study that explored whether the Big Five personality traits prospectively moderate the effects of medication beliefs on changes in adherence during the pandemic for a group of outpatients with psychosis or bipolar disorder. Methods. Thirteen outpatients undergoing routine face-to-face follow-up assessments during the pandemic were included (41 observations overall) and completed the Revised Italian Version of the Ten-Item Personality Inventory, the Beliefs about Medicines Questionnaire, the Morisky Medication Adherence Scale—8-item and the Beck Depression Inventory—II. Results. Participants had stronger concerns about their psychiatric medications rather than beliefs about their necessity, and adherence to medications was generally low. Participants who had more necessity beliefs than concerns had better adherence to medications. People scoring higher in Conscientiousness and Neuroticism traits and more concerned about the medication side effects had poorer adherence. Conclusions. These preliminary data suggest the importance of a careful assessment of the adherence to medications amongst people with psychosis/bipolar disorder during the pandemic. Interventions aimed to improve adherence might focus on patients’ medication beliefs and their Conscientiousness and Neuroticism personality traits.https://www.mdpi.com/2076-3425/12/10/1315Big Five personalityadherencebeliefs about medicationsCOVID-19 pandemicmental disordersstress
spellingShingle Fabio Ferretti
Arianna Goracci
Pier Francesco Laurenzi
Rossella Centola
Irene Crecchi
Aldo De Luca
Janette Monzillo
Omar Guidi
Giusy Sinigaglia
Giacomo Gualtieri
Lore Lorenzi
Alessandro Cuomo
Simone Bolognesi
Valter Travagli
Anna Coluccia
Andrea Fagiolini
Andrea Pozza
Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
Brain Sciences
Big Five personality
adherence
beliefs about medications
COVID-19 pandemic
mental disorders
stress
title Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
title_full Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
title_fullStr Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
title_full_unstemmed Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
title_short Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic
title_sort neuroticism and conscientiousness moderate the effect of oral medication beliefs on adherence of people with mental illness during the pandemic
topic Big Five personality
adherence
beliefs about medications
COVID-19 pandemic
mental disorders
stress
url https://www.mdpi.com/2076-3425/12/10/1315
work_keys_str_mv AT fabioferretti neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT ariannagoracci neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT pierfrancescolaurenzi neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT rossellacentola neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT irenecrecchi neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT aldodeluca neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT janettemonzillo neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT omarguidi neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT giusysinigaglia neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT giacomogualtieri neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT lorelorenzi neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT alessandrocuomo neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT simonebolognesi neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT valtertravagli neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT annacoluccia neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT andreafagiolini neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic
AT andreapozza neuroticismandconscientiousnessmoderatetheeffectoforalmedicationbeliefsonadherenceofpeoplewithmentalillnessduringthepandemic