Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns
Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2002-11-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/8/11/02-0284_article |
| _version_ | 1828487351223975936 |
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| author | Kashef Ijaz Zhenhua Yang H. Stewart Matthews Joseph H. Bates M. Donald Cave |
| author_facet | Kashef Ijaz Zhenhua Yang H. Stewart Matthews Joseph H. Bates M. Donald Cave |
| author_sort | Kashef Ijaz |
| collection | DOAJ |
| description | Molecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprint patterns (i.e., differing by a single band) has not been well documented. We used DNA fingerprinting, combined with conventional epidemiology, to show unsuspected patterns of tuberculosis transmission associated with three public bars in the same city. Among clustered TB cases, DNA fingerprinting analysis of isolates with similar and identical fingerprints helped us discover epidemiologic links missed during routine tuberculosis contact investigations. |
| first_indexed | 2024-12-11T09:49:08Z |
| format | Article |
| id | doaj.art-73c3a63c5cd84604b783a130c430fa15 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T09:49:08Z |
| publishDate | 2002-11-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-73c3a63c5cd84604b783a130c430fa152022-12-22T01:12:27ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592002-11-018111257125910.3201/eid0811.020284Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint PatternsKashef IjazZhenhua YangH. Stewart MatthewsJoseph H. BatesM. Donald CaveMolecular epidemiologic studies provide evidence of transmission of Mycobacterium tuberculosis within clusters of patients whose isolates share identical IS6110-DNA fingerprint patterns. However, M. tuberculosis transmission among patients whose isolates have similar but not identical DNA fingerprint patterns (i.e., differing by a single band) has not been well documented. We used DNA fingerprinting, combined with conventional epidemiology, to show unsuspected patterns of tuberculosis transmission associated with three public bars in the same city. Among clustered TB cases, DNA fingerprinting analysis of isolates with similar and identical fingerprints helped us discover epidemiologic links missed during routine tuberculosis contact investigations.https://wwwnc.cdc.gov/eid/article/8/11/02-0284_articleMycobacterium tuberculosisIS6110 RFLPmolecular epidemiologytuberculosis transmissionbarsUnited States |
| spellingShingle | Kashef Ijaz Zhenhua Yang H. Stewart Matthews Joseph H. Bates M. Donald Cave Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns Emerging Infectious Diseases Mycobacterium tuberculosis IS6110 RFLP molecular epidemiology tuberculosis transmission bars United States |
| title | Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns |
| title_full | Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns |
| title_fullStr | Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns |
| title_full_unstemmed | Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns |
| title_short | Mycobacterium tuberculosis Transmission between Cluster Members with Similar Fingerprint Patterns |
| title_sort | mycobacterium tuberculosis transmission between cluster members with similar fingerprint patterns |
| topic | Mycobacterium tuberculosis IS6110 RFLP molecular epidemiology tuberculosis transmission bars United States |
| url | https://wwwnc.cdc.gov/eid/article/8/11/02-0284_article |
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