The Identification of Nuclear FMRP Isoform Iso6 Partners

The Identification of Nuclear FMRP Isoform Iso6 Partners

A deficiency of FMRP, a canonical RNA-binding protein, causes the development of Fragile X Syndrome (FXS), which is characterised by multiple phenotypes, including neurodevelopmental disorders, intellectual disability, and autism. Due to the alternative splicing of the encoding <i>FMR1</i&g...

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Bibliographic Details
Main Authors: Nassim Ledoux, Emeline I. J. Lelong, Alexandre Simard, Samer Hussein, Pauline Adjibade, Jean-Philippe Lambert, Rachid Mazroui
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
FMRP
RNA-binding proteins
GFP-Trap
mass spectrometry
proteasome
Online Access:https://www.mdpi.com/2073-4409/12/24/2807

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