A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307—a truncated version of the V protein) provided superior protection against plague challenge compared to individ...

Full description

Bibliographic Details
Main Authors: Tonie E. Rocke, Brock Kingstad-Bakke, Willy Berlier, Jorge E. Osorio
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Vaccines
Subjects:
raccoon poxvirus
Yersinia pestis
plague
vaccine
prairie dogs
Online Access:http://www.mdpi.com/2076-393X/2/4/772

Similar Items

Similar Items