Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review

Myeloid sarcoma (MS) is an extramedullary hematopoietic tumor of immature myeloid cells. It is more common in males, and may present across a wide range of age groups. It rarely occurs in isolation and is chiefly associated with AML, of which it may be the first presentation. Most patients with MS w...

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Main Authors: Somayah Alsolami, Bayan Hafiz, Abeer Mehdar, Hatim Almaghraby
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Human Pathology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772736X22000391
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author Somayah Alsolami
Bayan Hafiz
Abeer Mehdar
Hatim Almaghraby
author_facet Somayah Alsolami
Bayan Hafiz
Abeer Mehdar
Hatim Almaghraby
author_sort Somayah Alsolami
collection DOAJ
description Myeloid sarcoma (MS) is an extramedullary hematopoietic tumor of immature myeloid cells. It is more common in males, and may present across a wide range of age groups. It rarely occurs in isolation and is chiefly associated with AML, of which it may be the first presentation. Most patients with MS will progress to AML within one year of diagnosis, but this can be delayed with early detection and treatment. Isolated MS is very rare, but can occur at any site in the body. MS in the pancreas is uncommon and can simulate the symptoms of pancreatitis or adenocarcinoma, making this a challenging diagnosis. Here, we present a case of MS diagnosed in a 12-year-old boy with no known history of AML. To our knowledge, this is the first reported case of isolated pancreatic myeloid sarcoma in Saudi Arabia.
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spelling doaj.art-73c898756b8f41e49d1a6e8fdfc852172022-12-22T00:42:10ZengElsevierHuman Pathology Reports2772-736X2022-06-0128300627Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature reviewSomayah Alsolami0Bayan Hafiz1Abeer Mehdar2Hatim Almaghraby3Department of Laboratory Medicine and Pathology, King Abdulaziz University, Jeddah, Saudi Arabia; Corresponding author.Department of Laboratory Medicine and Pathology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi ArabiaDepartment of Radiology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi ArabiaDepartment of Laboratory Medicine and Pathology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi ArabiaMyeloid sarcoma (MS) is an extramedullary hematopoietic tumor of immature myeloid cells. It is more common in males, and may present across a wide range of age groups. It rarely occurs in isolation and is chiefly associated with AML, of which it may be the first presentation. Most patients with MS will progress to AML within one year of diagnosis, but this can be delayed with early detection and treatment. Isolated MS is very rare, but can occur at any site in the body. MS in the pancreas is uncommon and can simulate the symptoms of pancreatitis or adenocarcinoma, making this a challenging diagnosis. Here, we present a case of MS diagnosed in a 12-year-old boy with no known history of AML. To our knowledge, this is the first reported case of isolated pancreatic myeloid sarcoma in Saudi Arabia.http://www.sciencedirect.com/science/article/pii/S2772736X22000391PancreasMyeloid sarcomaGranulocytic sarcoma
spellingShingle Somayah Alsolami
Bayan Hafiz
Abeer Mehdar
Hatim Almaghraby
Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
Human Pathology Reports
Pancreas
Myeloid sarcoma
Granulocytic sarcoma
title Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
title_full Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
title_fullStr Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
title_full_unstemmed Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
title_short Rare isolated pancreatic myeloid sarcoma in a pediatric patient – A case study with literature review
title_sort rare isolated pancreatic myeloid sarcoma in a pediatric patient a case study with literature review
topic Pancreas
Myeloid sarcoma
Granulocytic sarcoma
url http://www.sciencedirect.com/science/article/pii/S2772736X22000391
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AT abeermehdar rareisolatedpancreaticmyeloidsarcomainapediatricpatientacasestudywithliteraturereview
AT hatimalmaghraby rareisolatedpancreaticmyeloidsarcomainapediatricpatientacasestudywithliteraturereview