Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study

Background: The purpose of this study was to assess the risk of venous thromboembolism (VTE) and the potential need for thromboprophylaxis in patients with tuberculosis (TB). Methods: A total of 103 patients who underwent treatment for TB at the King Khalid University Hospital in Riyadh between Febr...

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Main Authors: Talal A Altuwaijri, Ghada K Alhindi, Noha M Al-Qattan, Sara K Alkharashi, Ali M Somily, Abdulmajeed H Altoijry
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=2;spage=205;epage=208;aulast=Altuwaijri
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author Talal A Altuwaijri
Ghada K Alhindi
Noha M Al-Qattan
Sara K Alkharashi
Ali M Somily
Abdulmajeed H Altoijry
author_facet Talal A Altuwaijri
Ghada K Alhindi
Noha M Al-Qattan
Sara K Alkharashi
Ali M Somily
Abdulmajeed H Altoijry
author_sort Talal A Altuwaijri
collection DOAJ
description Background: The purpose of this study was to assess the risk of venous thromboembolism (VTE) and the potential need for thromboprophylaxis in patients with tuberculosis (TB). Methods: A total of 103 patients who underwent treatment for TB at the King Khalid University Hospital in Riyadh between February 2015 to May 2018, the percentage of patients diagnosed with TB who developed VTE was assessed. This was a retrospective cohort study conducted at King Khalid University Hospital in Riyadh. Fisher's exact test was used to analyze the categorical variables.P < 0.05 was considered statistically significant. Results: Our data showed the prevalence of VTE in TB patients to be 2.93% (3/103). VTE occurred irrespective of the type of TB (pulmonary and/or extrapulmonary). All TB patients with VTE showed no significant association with factors such as human immunodeficiency virus coinfection, malignancy, and multidrug-resistant TB. Conclusion: Our study showed that TB patients in Saudi Arabia may be at a higher risk for developing VTE and should be carefully monitored as potential candidates for additional thromboprophylaxis; further studies are recommended to establish more reliable assessment and recommendations.
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spelling doaj.art-73cb00826311410eba82f36a3de3390f2022-12-22T00:07:59ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2020-01-019220520810.4103/ijmy.ijmy_28_20Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort StudyTalal A AltuwaijriGhada K AlhindiNoha M Al-QattanSara K AlkharashiAli M SomilyAbdulmajeed H AltoijryBackground: The purpose of this study was to assess the risk of venous thromboembolism (VTE) and the potential need for thromboprophylaxis in patients with tuberculosis (TB). Methods: A total of 103 patients who underwent treatment for TB at the King Khalid University Hospital in Riyadh between February 2015 to May 2018, the percentage of patients diagnosed with TB who developed VTE was assessed. This was a retrospective cohort study conducted at King Khalid University Hospital in Riyadh. Fisher's exact test was used to analyze the categorical variables.P < 0.05 was considered statistically significant. Results: Our data showed the prevalence of VTE in TB patients to be 2.93% (3/103). VTE occurred irrespective of the type of TB (pulmonary and/or extrapulmonary). All TB patients with VTE showed no significant association with factors such as human immunodeficiency virus coinfection, malignancy, and multidrug-resistant TB. Conclusion: Our study showed that TB patients in Saudi Arabia may be at a higher risk for developing VTE and should be carefully monitored as potential candidates for additional thromboprophylaxis; further studies are recommended to establish more reliable assessment and recommendations.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=2;spage=205;epage=208;aulast=Altuwaijrihuman immunodeficiency virus infectionmultidrug resistantsaudi arabiatuberculosisvenous thromboembolism
spellingShingle Talal A Altuwaijri
Ghada K Alhindi
Noha M Al-Qattan
Sara K Alkharashi
Ali M Somily
Abdulmajeed H Altoijry
Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
International Journal of Mycobacteriology
human immunodeficiency virus infection
multidrug resistant
saudi arabia
tuberculosis
venous thromboembolism
title Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
title_full Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
title_fullStr Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
title_full_unstemmed Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
title_short Occurrence of Venous Thromboembolism in Hospitalized Patients with Tuberculosis in Saudi Arabia: A Retrospective Cohort Study
title_sort occurrence of venous thromboembolism in hospitalized patients with tuberculosis in saudi arabia a retrospective cohort study
topic human immunodeficiency virus infection
multidrug resistant
saudi arabia
tuberculosis
venous thromboembolism
url http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=2;spage=205;epage=208;aulast=Altuwaijri
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