Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis

Objective: Evaluation of surgical, oncological and functional results in patients with prostate cancer and enlarged median lobe who underwent robot- assisted radical prostatectomy (RARP). Materials and Methods: Medical records of 489 patients who underwent RARP between August 2009 and December 20...

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Main Authors: Taner Kargi, Kamil Gokhan Seker, Abdullah Hizir Yavuzsan, Bugra Dogukan Torer, Muhammed Yusuf Demir, Deniz Noyan Ozlu, Serdar Karadag, Selcuk Sahin, Volkan Tugcu, Ali Ihsan Tasci
Format: Article
Language:English
Published: Ekrem Güner 2022-05-01
Series:Grand Journal of Urology
Subjects:
Online Access:https://grandjournalofurology.com/uploads/pdf/pdf_GJU_56.pdf
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author Taner Kargi
Kamil Gokhan Seker
Abdullah Hizir Yavuzsan
Bugra Dogukan Torer
Muhammed Yusuf Demir
Deniz Noyan Ozlu
Serdar Karadag
Selcuk Sahin
Volkan Tugcu
Ali Ihsan Tasci
author_facet Taner Kargi
Kamil Gokhan Seker
Abdullah Hizir Yavuzsan
Bugra Dogukan Torer
Muhammed Yusuf Demir
Deniz Noyan Ozlu
Serdar Karadag
Selcuk Sahin
Volkan Tugcu
Ali Ihsan Tasci
author_sort Taner Kargi
collection DOAJ
description Objective: Evaluation of surgical, oncological and functional results in patients with prostate cancer and enlarged median lobe who underwent robot- assisted radical prostatectomy (RARP). Materials and Methods: Medical records of 489 patients who underwent RARP between August 2009 and December 2013 were retrospectively evaluated. Among them, 40 patients who had enlarged median lobe were included in Group 1. Forty patients without median lobe hyperplasia were included with matched analysis (Group 2). Patients who were followed up for 12 months were assessed. Results: No significant differences were found between the two groups in terms of demographic values, erectile function, preoperative PSA levels, prostate dimensions, distribution of clinical stages, Gleason scores and D"Amico risk classification (p˃0,05). Perioperative data revealed that mean operative times were 219.9 ± 64.5 (130-360) min and 185.6 ± 57.1 (120-355) min in Groups 1 and 2, respectively which was significantly prolonged in Group 1 (p˂0.05). Bladder neck reconstruction was performed in Groups 1 (n=14: 5%) and 2 (n=1: 3%). Rates of full continence after removal of urethral catheter on day 7 and at the end of months 1, 3, 6 and 12 were similar in Groups 1 and 2 (p˃0.05). Rates of potency and biochemical recurrence were similar at the end of the postoperative 6 months and one year in Groups 1 and 2 (p˃0.05). Conclusion: RARP in patients with prostate cancer with an enlarged median lobe is a challenging operation with significantly longer operative times. With its inherent procedural difficulties, RARP is a good treatment option in patients with prostate cancer and an enlarged median lobe with its successful surgical dissection and anastomosis possibilities.
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spelling doaj.art-73cb1d6847164fa38720c04f263a09512023-03-16T09:13:53ZengEkrem GünerGrand Journal of Urology2757-71632022-05-0122647110.5505/GJU.2022.68077Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched AnalysisTaner Kargi0https://orcid.org/0000-0001-5874-3489Kamil Gokhan Seker1https://orcid.org/0000-0003-4449-9037Abdullah Hizir Yavuzsan2https://orcid.org/0000-0002-1561-895XBugra Dogukan Torer3https://orcid.org/0000-0003-1847-6798Muhammed Yusuf Demir4https://orcid.org/0000-0003-0927-3593Deniz Noyan Ozlu5https://orcid.org/0000-0003-2435-5482Serdar Karadag6https://orcid.org/0000-0002-1420-4536Selcuk Sahin7https://orcid.org/0000-0002-0903-320XVolkan Tugcu8https://orcid.org/0000-0002-4136-7584Ali Ihsan Tasci9https://orcid.org/0000-0002-6943-6676Department of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, Liv Hospital Vadistanbul, Istanbul, TurkeyDepartment of Urology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, Reyhanlı State Hospital, Hatay, TurkeyDepartment of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyDepartment of Urology, Liv Hospital Vadistanbul, Istanbul, TurkeyDepartment of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, TurkeyObjective: Evaluation of surgical, oncological and functional results in patients with prostate cancer and enlarged median lobe who underwent robot- assisted radical prostatectomy (RARP). Materials and Methods: Medical records of 489 patients who underwent RARP between August 2009 and December 2013 were retrospectively evaluated. Among them, 40 patients who had enlarged median lobe were included in Group 1. Forty patients without median lobe hyperplasia were included with matched analysis (Group 2). Patients who were followed up for 12 months were assessed. Results: No significant differences were found between the two groups in terms of demographic values, erectile function, preoperative PSA levels, prostate dimensions, distribution of clinical stages, Gleason scores and D"Amico risk classification (p˃0,05). Perioperative data revealed that mean operative times were 219.9 ± 64.5 (130-360) min and 185.6 ± 57.1 (120-355) min in Groups 1 and 2, respectively which was significantly prolonged in Group 1 (p˂0.05). Bladder neck reconstruction was performed in Groups 1 (n=14: 5%) and 2 (n=1: 3%). Rates of full continence after removal of urethral catheter on day 7 and at the end of months 1, 3, 6 and 12 were similar in Groups 1 and 2 (p˃0.05). Rates of potency and biochemical recurrence were similar at the end of the postoperative 6 months and one year in Groups 1 and 2 (p˃0.05). Conclusion: RARP in patients with prostate cancer with an enlarged median lobe is a challenging operation with significantly longer operative times. With its inherent procedural difficulties, RARP is a good treatment option in patients with prostate cancer and an enlarged median lobe with its successful surgical dissection and anastomosis possibilities.https://grandjournalofurology.com/uploads/pdf/pdf_GJU_56.pdfmedian lobeprostate cancerrobot-assisted radical prostatectomy
spellingShingle Taner Kargi
Kamil Gokhan Seker
Abdullah Hizir Yavuzsan
Bugra Dogukan Torer
Muhammed Yusuf Demir
Deniz Noyan Ozlu
Serdar Karadag
Selcuk Sahin
Volkan Tugcu
Ali Ihsan Tasci
Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
Grand Journal of Urology
median lobe
prostate cancer
robot-assisted radical prostatectomy
title Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
title_full Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
title_fullStr Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
title_full_unstemmed Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
title_short Robot-Assisted Radical Prostatectomy in Patients with Enlarged Median Lobe: Matched Analysis
title_sort robot assisted radical prostatectomy in patients with enlarged median lobe matched analysis
topic median lobe
prostate cancer
robot-assisted radical prostatectomy
url https://grandjournalofurology.com/uploads/pdf/pdf_GJU_56.pdf
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AT bugradogukantorer robotassistedradicalprostatectomyinpatientswithenlargedmedianlobematchedanalysis
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