Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance

Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance

Epilepsy is a neurological disorder affecting around 1%–2% of population worldwide and its treatment includes use of antiepileptic drugs to control seizures. Failure to respond to antiepileptic drug therapy is a major clinical problem and over expression of ATP-binding cassette transporters is consi...

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Bibliographic Details
Main Authors: Gurpreet Kaur Grewal, Samiksha Kukal, Neha Kanojia, Luciano Saso, Shrikant Kukreti, Ritushree Kukreti
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
epilepsy
ABC transporters
oxidative stress
antiepileptic drugs
pharmacoresistance
Online Access:http://www.mdpi.com/1420-3049/22/3/365

Internet

http://www.mdpi.com/1420-3049/22/3/365

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