Acetone-precipitated zein protein hydrolysates from blue-maize selectively target hepatocellular carcinoma and fibroblasts in a dose-dependent manner

Acetone-precipitated zein protein hydrolysates from blue-maize selectively target hepatocellular carcinoma and fibroblasts in a dose-dependent manner

Herein, we investigated the effects of acetone precipitation on the bioactivity of blue-maize zein hydrolysates (BmapZDH) against hepatocarcinoma (HepG2) and non-tumor cells (fibroblasts). Zein proteins were extracted from blue-maize flour hydrolyzed with Alcalase for 6 h, and the peptide fractions...

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Bibliographic Details
Main Authors: Plinio A. Trinidad-Calderón, Laura Margarita López-Castillo, Jorge L. Díaz-Gómez, Rodrigo Balam Muñoz Soto, Fabiola Castorena-Torres, Silverio García-Lara
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Food Hydrocolloids for Health
Subjects:
Zein
Hydrolysate
Cancer
Hepatocarcinoma
Fibroblasts
Online Access:http://www.sciencedirect.com/science/article/pii/S2667025922000528

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