Entomologic and Virologic Investigation of Chikungunya, Singapore
Local transmission of chikungunya, a debilitating mosquito-borne viral disease, was first reported in Singapore in January 2008. After 3 months of absence, locally acquired Chikungunya cases resurfaced in May 2008, causing an outbreak that resulted in a total of 231 cases by September 2008. The circ...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2009-08-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/15/8/08-1486_article |
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| author | Lee-Ching Ng Li-Kiang Tan Cheong-Huat Tan Sharon S.Y. Tan Hapuarachchige C. Hapuarachchi Kwoon-Yong Pok Yee-Ling Lai Sai-Gek Lam-Phua Göran Bucht Raymond T.P. Lin Yee-Sin Leo Boon-Hian Tan Hwi-Kwang Han Peng-Lim S Ooi Lyn James Seow-Poh Khoo |
| author_facet | Lee-Ching Ng Li-Kiang Tan Cheong-Huat Tan Sharon S.Y. Tan Hapuarachchige C. Hapuarachchi Kwoon-Yong Pok Yee-Ling Lai Sai-Gek Lam-Phua Göran Bucht Raymond T.P. Lin Yee-Sin Leo Boon-Hian Tan Hwi-Kwang Han Peng-Lim S Ooi Lyn James Seow-Poh Khoo |
| author_sort | Lee-Ching Ng |
| collection | DOAJ |
| description | Local transmission of chikungunya, a debilitating mosquito-borne viral disease, was first reported in Singapore in January 2008. After 3 months of absence, locally acquired Chikungunya cases resurfaced in May 2008, causing an outbreak that resulted in a total of 231 cases by September 2008. The circulating viruses were related to East, Central, and South African genotypes that emerged in the Indian Ocean region in 2005. The first local outbreak was due to a wild-type virus (alanine at codon 226 of the envelope 1 gene) and occurred in an area where Aedes aegypti mosquitoes were the primary vector. Strains isolated during subsequent outbreaks showed alanine to valine substitution (A226V) and largely spread in areas predominated by Ae. albopictus mosquitoes. These findings led to a revision of the current vector control strategy in Singapore. This report highlights the use of entomologic and virologic data to assist in the control of chikungunya in disease-endemic areas. |
| first_indexed | 2024-04-12T06:47:00Z |
| format | Article |
| id | doaj.art-73cfecd800c04ca880537317710bc272 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T06:47:00Z |
| publishDate | 2009-08-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-73cfecd800c04ca880537317710bc2722022-12-22T03:43:31ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-08-011581243124910.3201/eid1508.081486Entomologic and Virologic Investigation of Chikungunya, SingaporeLee-Ching NgLi-Kiang TanCheong-Huat TanSharon S.Y. TanHapuarachchige C. HapuarachchiKwoon-Yong PokYee-Ling LaiSai-Gek Lam-PhuaGöran BuchtRaymond T.P. LinYee-Sin LeoBoon-Hian TanHwi-Kwang HanPeng-Lim S OoiLyn JamesSeow-Poh KhooLocal transmission of chikungunya, a debilitating mosquito-borne viral disease, was first reported in Singapore in January 2008. After 3 months of absence, locally acquired Chikungunya cases resurfaced in May 2008, causing an outbreak that resulted in a total of 231 cases by September 2008. The circulating viruses were related to East, Central, and South African genotypes that emerged in the Indian Ocean region in 2005. The first local outbreak was due to a wild-type virus (alanine at codon 226 of the envelope 1 gene) and occurred in an area where Aedes aegypti mosquitoes were the primary vector. Strains isolated during subsequent outbreaks showed alanine to valine substitution (A226V) and largely spread in areas predominated by Ae. albopictus mosquitoes. These findings led to a revision of the current vector control strategy in Singapore. This report highlights the use of entomologic and virologic data to assist in the control of chikungunya in disease-endemic areas.https://wwwnc.cdc.gov/eid/article/15/8/08-1486_articleChikungunyachikungunya virussurveillanceentomologyvirologysequencing |
| spellingShingle | Lee-Ching Ng Li-Kiang Tan Cheong-Huat Tan Sharon S.Y. Tan Hapuarachchige C. Hapuarachchi Kwoon-Yong Pok Yee-Ling Lai Sai-Gek Lam-Phua Göran Bucht Raymond T.P. Lin Yee-Sin Leo Boon-Hian Tan Hwi-Kwang Han Peng-Lim S Ooi Lyn James Seow-Poh Khoo Entomologic and Virologic Investigation of Chikungunya, Singapore Emerging Infectious Diseases Chikungunya chikungunya virus surveillance entomology virology sequencing |
| title | Entomologic and Virologic Investigation of Chikungunya, Singapore |
| title_full | Entomologic and Virologic Investigation of Chikungunya, Singapore |
| title_fullStr | Entomologic and Virologic Investigation of Chikungunya, Singapore |
| title_full_unstemmed | Entomologic and Virologic Investigation of Chikungunya, Singapore |
| title_short | Entomologic and Virologic Investigation of Chikungunya, Singapore |
| title_sort | entomologic and virologic investigation of chikungunya singapore |
| topic | Chikungunya chikungunya virus surveillance entomology virology sequencing |
| url | https://wwwnc.cdc.gov/eid/article/15/8/08-1486_article |
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