Trends for in-office usage of pharmacological sedation agents in India: A narrative review

Background and Aims: Conscious sedation plays a significant role in in-office pharmacological behavior management for short-term procedures in children and apprehensive adults. The advantage conscious sedation provides is by improving quality of care provided by decreasing pain and anxiety while mai...

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Main Authors: Sakshi Joshi, Anil Gupta, Shalini Garg, Shikha Dogra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=18;epage=27;aulast=Joshi
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author Sakshi Joshi
Anil Gupta
Shalini Garg
Shikha Dogra
author_facet Sakshi Joshi
Anil Gupta
Shalini Garg
Shikha Dogra
author_sort Sakshi Joshi
collection DOAJ
description Background and Aims: Conscious sedation plays a significant role in in-office pharmacological behavior management for short-term procedures in children and apprehensive adults. The advantage conscious sedation provides is by improving quality of care provided by decreasing pain and anxiety while maintaining a patent airway and adequate spontaneous ventilation. Methodology: Present review was conducted to evaluate recent trends regarding use of in-office pharmacological sedation agents in India. A rigorous search was conducted through five electronic databases namely PubMed, Scopus, Web of Science, Cochrane Database, and CTRI (Clinical Trial Registry – India). The search period was defined to be last 5 years, that is, from 1st January 2014 to 31st July 2019. Terminologies “Conscious Sedation,” “In-office Sedation,” “Midazolam,” “Nitrous Oxide,” “India” were included in the search. The Boolean Operation “OR” and “AND” were applied to combine the terminologies. Results: A total of 20 studies were identified following strict inclusion and exclusion criteria. The included studies were evaluated for study design, speciality involved, number of individuals and their age groups, drugs compared along with route and dosage, procedures undertaken, place of study and results. Dental fraternity (13) had more number of trials conducted as compared to medical fraternity (7) in the stimulated period, with South Indian region having maximum trials registered or published. Conclusion: Midazolam was observed to the drug of choice for in-office sedation procedures in Indian Scenario. The limitation of study is that the published clinical studies are limited to a few states of India.
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spelling doaj.art-73d1d342951f4ade8ca5ff2e37caaf422022-12-22T00:32:57ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852022-01-01381182710.4103/joacp.JOACP_146_20Trends for in-office usage of pharmacological sedation agents in India: A narrative reviewSakshi JoshiAnil GuptaShalini GargShikha DograBackground and Aims: Conscious sedation plays a significant role in in-office pharmacological behavior management for short-term procedures in children and apprehensive adults. The advantage conscious sedation provides is by improving quality of care provided by decreasing pain and anxiety while maintaining a patent airway and adequate spontaneous ventilation. Methodology: Present review was conducted to evaluate recent trends regarding use of in-office pharmacological sedation agents in India. A rigorous search was conducted through five electronic databases namely PubMed, Scopus, Web of Science, Cochrane Database, and CTRI (Clinical Trial Registry – India). The search period was defined to be last 5 years, that is, from 1st January 2014 to 31st July 2019. Terminologies “Conscious Sedation,” “In-office Sedation,” “Midazolam,” “Nitrous Oxide,” “India” were included in the search. The Boolean Operation “OR” and “AND” were applied to combine the terminologies. Results: A total of 20 studies were identified following strict inclusion and exclusion criteria. The included studies were evaluated for study design, speciality involved, number of individuals and their age groups, drugs compared along with route and dosage, procedures undertaken, place of study and results. Dental fraternity (13) had more number of trials conducted as compared to medical fraternity (7) in the stimulated period, with South Indian region having maximum trials registered or published. Conclusion: Midazolam was observed to the drug of choice for in-office sedation procedures in Indian Scenario. The limitation of study is that the published clinical studies are limited to a few states of India.http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=18;epage=27;aulast=Joshiconscious sedationindiamidazolam
spellingShingle Sakshi Joshi
Anil Gupta
Shalini Garg
Shikha Dogra
Trends for in-office usage of pharmacological sedation agents in India: A narrative review
Journal of Anaesthesiology Clinical Pharmacology
conscious sedation
india
midazolam
title Trends for in-office usage of pharmacological sedation agents in India: A narrative review
title_full Trends for in-office usage of pharmacological sedation agents in India: A narrative review
title_fullStr Trends for in-office usage of pharmacological sedation agents in India: A narrative review
title_full_unstemmed Trends for in-office usage of pharmacological sedation agents in India: A narrative review
title_short Trends for in-office usage of pharmacological sedation agents in India: A narrative review
title_sort trends for in office usage of pharmacological sedation agents in india a narrative review
topic conscious sedation
india
midazolam
url http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=18;epage=27;aulast=Joshi
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AT shikhadogra trendsforinofficeusageofpharmacologicalsedationagentsinindiaanarrativereview