Fusogenic Hybrid Extracellular Vesicles with PD-1 Membrane Proteins for the Cytosolic Delivery of Cargos

Fusogenic Hybrid Extracellular Vesicles with PD-1 Membrane Proteins for the Cytosolic Delivery of Cargos

Extracellular vesicles (EVs) are cell-derived lipid membrane capsules that can deliver functional molecules, such as nucleic acids, to target cells. Currently, the application of EVs is limited because of the difficulty of loading cargo into EVs. We constructed hybrid EVs by the fusion of liposomes...

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Bibliographic Details
Main Authors: Raga Ishikawa, Shosuke Yoshida, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
extracellular vesicle
baculovirus expression system
liposome
membrane fusion
programmed cell death 1
cytosolic delivery
Online Access:https://www.mdpi.com/2072-6694/14/11/2635

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