Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin.
Streptococcus suis serotype 2 (SS2) is a major zoonotic pathogen resulting in manifestations as pneumonia and septic shock. The upper respiratory tract is typically thought to be the main colonization and entry site of SS2 in pigs, but the mechanism through which it penetrates the respiratory barrie...
Main Authors: | Yu Meng, Qing Wang, Zhe Ma, Weiyi Li, Kai Niu, Ting Zhu, Huixing Lin, Chengping Lu, Hongjie Fan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-08-01
|
Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1010765 |
Similar Items
-
Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection
by: Yu Meng, et al.
Published: (2023-01-01) -
Porcine circovirus type 2 exploits JNK-mediated disruption of tight junctions to facilitate Streptococcus suis translocation across the tracheal epithelium
by: Qing Wang, et al.
Published: (2020-02-01) -
Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium
by: Colin C. Kietzman, et al.
Published: (2016-02-01) -
Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation
by: Qing Wang, et al.
Published: (2021-10-01) -
Building blocks and blueprints for bacterial autolysins.
by: Spencer J Mitchell, et al.
Published: (2021-04-01)