Characterization of the complete mitochondrial genome of the lung fluke, Paragonimus heterotremus

In this study, the complete mitochondrial genome of human lung fluke, Paragonimus heterotremus, was recovered through Illumina sequencing data. This complete mitochondrial genome of P. heterotremus is 13,927 bp in length and has a base composition of A (16.6%), T (41.8%), C (13.%), G (28.4%), demons...

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Bibliographic Details
Main Authors: Lei Qian, Ping Zhou, Weilin Li, Huaiping Wang, Tianjie Miao, Longgang Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Mitochondrial DNA. Part B. Resources
Subjects:
Online Access:http://dx.doi.org/10.1080/23802359.2018.1462119
Description
Summary:In this study, the complete mitochondrial genome of human lung fluke, Paragonimus heterotremus, was recovered through Illumina sequencing data. This complete mitochondrial genome of P. heterotremus is 13,927 bp in length and has a base composition of A (16.6%), T (41.8%), C (13.%), G (28.4%), demonstrating an obvious bias of high AT content (58.4%). The mitochondrial genome contains a typically conserved structure, encoding 12 protein-coding genes (PCGs), 22 transfer RNA genes (tRNA), 2 ribosomal RNA genes (12S rRNA and 16S rRNA) and a control region (D-loop region). All PCGs were located on the H-strand. ND4 gene and ND4L gene were overlapped by 39 bp. The nucleotide sequence of 12 PCGs of P. heterotremus and other 10 parasite species were used for phylogenetic analysis. The result indicated P. heterotremus a relative close relationship with species Paragonimus westermani (AF219379.2).
ISSN:2380-2359