PgxSAVy: A tool for comprehensive evaluation of variant peptide quality in proteogenomics – catching the (un)usual suspects
Variant peptides resulting from single nucleotide polymorphisms (SNPs) can lead to aberrant protein functions and have translational potential for disease diagnosis and personalized therapy. Variant peptides detected by proteogenomics are fraught with high number of false positives, but there is no...
Main Authors: | Anurag Raj, Suruchi Aggarwal, Prateek Singh, Amit Kumar Yadav, Debasis Dash |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-12-01
|
Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S200103702300507X |
Similar Items
-
Evolution of HLA-B Pharmacogenomics and the Importance of PGx Data Integration in Health Care System: A 10 Years Retrospective Study in Thailand
by: Napatrupron Koomdee, et al.
Published: (2022-04-01) -
Quantitative Proteogenomic Characterization of Inflamed Murine Colon Tissue Using an Integrated Discovery, Verification, and Validation Proteogenomic Workflow
by: Andrew T. Rajczewski, et al.
Published: (2022-04-01) -
Variant biomarker discovery using mass spectrometry-based proteogenomics
by: Luke Reilly, et al.
Published: (2023-04-01) -
ASSISTING TEACHERS IN DESIGNING SOMATIC AUDITORY VISUAL INTELLECTUAL (SAVI) LEARNING MODEL
by: Arbis Arbis
Published: (2021-01-01) -
Proteogenomics unveils mechanistic insights to precision oncology
by: Yongchao Dou, et al.
Published: (2023-11-01)