Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

Abstract Background Histidine-rich protein-2 (HRP2)-based rapid diagnostic tests (RDTs) are the only RDTs recommended for malaria diagnosis in Uganda. However, the emergence of Plasmodium falciparum histidine rich protein 2 and 3 (pfhrp2 and pfhrp3) gene deletions threatens their usefulness as malar...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Agaba B. Bosco, Karen Anderson, Karryn Gresty, Christiane Prosser, David Smith, Joaniter I. Nankabirwa, Sam Nsobya, Adoke Yeka, Jimmy Opigo, Samuel Gonahasa, Rhoda Namubiru, Emmanuel Arinaitwe, Paul Mbaka, John Kissa, Sungho Won, Bora Lee, Chae Seung Lim, Charles Karamagi, Jane Cunningham, Joan K. Nakayaga, Moses R. Kamya, Qin Cheng
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: BMC 2020-08-01
Sarja:Malaria Journal
Aiheet:
Malaria rapid diagnostic tests
Plasmodium falciparum
Histidine rich protein 2
Histidine rich protein 3
Gene deletion
Deoxyribonucleic acid
Linkit:http://link.springer.com/article/10.1186/s12936-020-03362-x

Internet

http://link.springer.com/article/10.1186/s12936-020-03362-x

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