The complete local genotype–phenotype landscape for the alternative splicing of a human exon
Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11558 |
| _version_ | 1818978109933748224 |
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| author | Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner |
| author_facet | Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner |
| author_sort | Philippe Julien |
| collection | DOAJ |
| description | Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species. |
| first_indexed | 2024-12-20T16:38:25Z |
| format | Article |
| id | doaj.art-73ea67a542874df4ab8caf4583215cb2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:38:25Z |
| publishDate | 2016-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-73ea67a542874df4ab8caf4583215cb22022-12-21T19:33:05ZengNature PortfolioNature Communications2041-17232016-05-01711810.1038/ncomms11558The complete local genotype–phenotype landscape for the alternative splicing of a human exonPhilippe Julien0Belén Miñana1Pablo Baeza-Centurion2Juan Valcárcel3Ben Lehner4EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and TechnologyUniversitat Pompeu Fabra (UPF)EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and TechnologyUniversitat Pompeu Fabra (UPF)EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and TechnologyGenotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.https://doi.org/10.1038/ncomms11558 |
| spellingShingle | Philippe Julien Belén Miñana Pablo Baeza-Centurion Juan Valcárcel Ben Lehner The complete local genotype–phenotype landscape for the alternative splicing of a human exon Nature Communications |
| title | The complete local genotype–phenotype landscape for the alternative splicing of a human exon |
| title_full | The complete local genotype–phenotype landscape for the alternative splicing of a human exon |
| title_fullStr | The complete local genotype–phenotype landscape for the alternative splicing of a human exon |
| title_full_unstemmed | The complete local genotype–phenotype landscape for the alternative splicing of a human exon |
| title_short | The complete local genotype–phenotype landscape for the alternative splicing of a human exon |
| title_sort | complete local genotype phenotype landscape for the alternative splicing of a human exon |
| url | https://doi.org/10.1038/ncomms11558 |
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