Timosaponin AIII Inhibits Migration and Invasion Abilities in Human Cervical Cancer Cells through Inactivation of p38 MAPK-Mediated uPA Expression In Vitro and In Vivo

Timosaponin AIII Inhibits Migration and Invasion Abilities in Human Cervical Cancer Cells through Inactivation of p38 MAPK-Mediated uPA Expression In Vitro and In Vivo

Cervical cancer is one of the most common gynecologic cancers globally that require novel approaches. Timosaponin AIII (TSAIII) is a steroidal saponin that displays beneficial effects in antitumor activities. However, the effect of TSAIII on human cervical cancer remains unknown. In this study, we f...

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Bibliographic Details
Main Authors: Hung-Ju Chien, Chung-Jung Liu, Tsung-Ho Ying, Pei-Ju Wu, Jiunn-Wei Wang, Yi-Hsuan Ting, Yi-Hsien Hsieh, Shih-Chiang Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
Timosaponin AIII
human cervical cancer
metastasis
p38 MAPK
uPA
Online Access:https://www.mdpi.com/2072-6694/15/1/37

Internet

https://www.mdpi.com/2072-6694/15/1/37

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