Research progress of autophagy in retinal and eye diseases
Maintaining the homeostasis of intracellular components degradation and recycling, autophagy is a critical control mechanism of cellular quality. It promotes the degradation of cell components to provide nutrients and energy for cellular metabolism in stress response. The retina is a light-sensitive...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2023-10-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2023/10/202310012.pdf |
| _version_ | 1797681998858289152 |
|---|---|
| author | Si-Yu Zeng Lei Du Yi-Qiao Xing |
| author_facet | Si-Yu Zeng Lei Du Yi-Qiao Xing |
| author_sort | Si-Yu Zeng |
| collection | DOAJ |
| description | Maintaining the homeostasis of intracellular components degradation and recycling, autophagy is a critical control mechanism of cellular quality. It promotes the degradation of cell components to provide nutrients and energy for cellular metabolism in stress response. The retina is a light-sensitive tissue that transduces and processes visual images in the eye, and it has a high demand for substances and energy. Basal autophagy is essential for holding retinal homeostasis and the normal function of the visual system. Therefore, the latest studies that investigating the participation of autophagy in eye diseases such as glaucoma, age-related macular degeneration, diabetic retinopathy, retinal dystrophies, and retinal detachment were summarized, providing a theoretical basis for the future treatment of eye diseases by regulating autophagy. |
| first_indexed | 2024-03-11T23:53:10Z |
| format | Article |
| id | doaj.art-73eea55f12894ba3bd03dd404d34f461 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-03-11T23:53:10Z |
| publishDate | 2023-10-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-73eea55f12894ba3bd03dd404d34f4612023-09-19T03:02:27ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232023-10-0123101662166610.3980/j.issn.1672-5123.2023.10.12202310012Research progress of autophagy in retinal and eye diseasesSi-Yu Zeng0Lei Du1Yi-Qiao Xing2Eye Center,Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaEye Center,Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaEye Center,Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, ChinaMaintaining the homeostasis of intracellular components degradation and recycling, autophagy is a critical control mechanism of cellular quality. It promotes the degradation of cell components to provide nutrients and energy for cellular metabolism in stress response. The retina is a light-sensitive tissue that transduces and processes visual images in the eye, and it has a high demand for substances and energy. Basal autophagy is essential for holding retinal homeostasis and the normal function of the visual system. Therefore, the latest studies that investigating the participation of autophagy in eye diseases such as glaucoma, age-related macular degeneration, diabetic retinopathy, retinal dystrophies, and retinal detachment were summarized, providing a theoretical basis for the future treatment of eye diseases by regulating autophagy.http://ies.ijo.cn/cn_publish/2023/10/202310012.pdfautophagyretinaretinal ganglion cellsphotoreceptor |
| spellingShingle | Si-Yu Zeng Lei Du Yi-Qiao Xing Research progress of autophagy in retinal and eye diseases Guoji Yanke Zazhi autophagy retina retinal ganglion cells photoreceptor |
| title | Research progress of autophagy in retinal and eye diseases |
| title_full | Research progress of autophagy in retinal and eye diseases |
| title_fullStr | Research progress of autophagy in retinal and eye diseases |
| title_full_unstemmed | Research progress of autophagy in retinal and eye diseases |
| title_short | Research progress of autophagy in retinal and eye diseases |
| title_sort | research progress of autophagy in retinal and eye diseases |
| topic | autophagy retina retinal ganglion cells photoreceptor |
| url | http://ies.ijo.cn/cn_publish/2023/10/202310012.pdf |
| work_keys_str_mv | AT siyuzeng researchprogressofautophagyinretinalandeyediseases AT leidu researchprogressofautophagyinretinalandeyediseases AT yiqiaoxing researchprogressofautophagyinretinalandeyediseases |