An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant
This article describes the synthesis of novel dihydropyrimidone derivatives that have been paid attention in organic, medicinal, dyes and many other chemistry disciplines. Here we have developed an efficient triple cascade process to prepare novel disperses dyes with dihydropyrimidine-thiones scaffo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622000819 |
| _version_ | 1811178133292843008 |
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| author | Paresh N. Patel Nilam C. Patel Dipen H. Desai |
| author_facet | Paresh N. Patel Nilam C. Patel Dipen H. Desai |
| author_sort | Paresh N. Patel |
| collection | DOAJ |
| description | This article describes the synthesis of novel dihydropyrimidone derivatives that have been paid attention in organic, medicinal, dyes and many other chemistry disciplines. Here we have developed an efficient triple cascade process to prepare novel disperses dyes with dihydropyrimidine-thiones scaffold. These 3, 4-dihydropyrimidin-2-(1H)-thione derivatives were prepared by simple triple cascade reaction via formal [1+2+3] cyclization among 2-hydroxy-1, 4-naphthoquinone, thiourea and various aromatic aldehyde. This process has varied substrate scope and shortened reaction duration with isolated yield up to 95% resulting in situ formation of one carbon–carbon as well as two carbon–nitrogen bonds. The structures of all the prepared molecules are confirmed with NMR, HRMS and IR spectroscopies. The color properties, UV visible spectral studies are also performed with all the prepared molecules. |
| first_indexed | 2024-04-11T06:14:10Z |
| format | Article |
| id | doaj.art-73efbd641a414f10a7773c2f144fd843 |
| institution | Directory Open Access Journal |
| issn | 2211-7156 |
| language | English |
| last_indexed | 2024-04-11T06:14:10Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj.art-73efbd641a414f10a7773c2f144fd8432022-12-22T04:41:08ZengElsevierResults in Chemistry2211-71562022-01-014100362An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorantParesh N. Patel0Nilam C. Patel1Dipen H. Desai2Corresponding author.; Laboratory of Bio-Organic Chemistry, Tarsadia Institute of Chemical Science (TICS), Uka Tarsadia University, Bardoli 394 350, Gujarat, IndiaLaboratory of Bio-Organic Chemistry, Tarsadia Institute of Chemical Science (TICS), Uka Tarsadia University, Bardoli 394 350, Gujarat, IndiaLaboratory of Bio-Organic Chemistry, Tarsadia Institute of Chemical Science (TICS), Uka Tarsadia University, Bardoli 394 350, Gujarat, IndiaThis article describes the synthesis of novel dihydropyrimidone derivatives that have been paid attention in organic, medicinal, dyes and many other chemistry disciplines. Here we have developed an efficient triple cascade process to prepare novel disperses dyes with dihydropyrimidine-thiones scaffold. These 3, 4-dihydropyrimidin-2-(1H)-thione derivatives were prepared by simple triple cascade reaction via formal [1+2+3] cyclization among 2-hydroxy-1, 4-naphthoquinone, thiourea and various aromatic aldehyde. This process has varied substrate scope and shortened reaction duration with isolated yield up to 95% resulting in situ formation of one carbon–carbon as well as two carbon–nitrogen bonds. The structures of all the prepared molecules are confirmed with NMR, HRMS and IR spectroscopies. The color properties, UV visible spectral studies are also performed with all the prepared molecules.http://www.sciencedirect.com/science/article/pii/S2211715622000819Triple cascade reaction[1+2+3] cyclizationLawsoneDihydropyrimidine-thionesDisperse dyes |
| spellingShingle | Paresh N. Patel Nilam C. Patel Dipen H. Desai An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant Results in Chemistry Triple cascade reaction [1+2+3] cyclization Lawsone Dihydropyrimidine-thiones Disperse dyes |
| title | An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant |
| title_full | An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant |
| title_fullStr | An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant |
| title_full_unstemmed | An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant |
| title_short | An efficient triple cascade process for synthesis of novel disperse dyes from lawsone: A modification of natural colorant |
| title_sort | efficient triple cascade process for synthesis of novel disperse dyes from lawsone a modification of natural colorant |
| topic | Triple cascade reaction [1+2+3] cyclization Lawsone Dihydropyrimidine-thiones Disperse dyes |
| url | http://www.sciencedirect.com/science/article/pii/S2211715622000819 |
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