Partial Agonistic Actions of Sex Hormone Steroids on TRPM3 Function

Partial Agonistic Actions of Sex Hormone Steroids on TRPM3 Function

Sex hormone steroidal drugs were reported to have modulating actions on the ion channel TRPM3. Pregnenolone sulphate (PS) presents the most potent known endogenous chemical agonist of TRPM3 and affects several gating modes of the channel. These includes a synergistic action of PS and high temperatur...

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Bibliographic Details
Main Authors: Eleonora Persoons, Sara Kerselaers, Thomas Voets, Joris Vriens, Katharina Held
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
transient receptor potential channel
TRPM3
steroid
DHEAS
estradiol
progesterone
Online Access:https://www.mdpi.com/1422-0067/22/24/13652

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