Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review
In recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.1003959/full |
| _version_ | 1797945404807970816 |
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| author | Chi Xue Yuwei Du Yuegang Li Huimian Xu Zhi Zhu |
| author_facet | Chi Xue Yuwei Du Yuegang Li Huimian Xu Zhi Zhu |
| author_sort | Chi Xue |
| collection | DOAJ |
| description | In recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predictors of therapeutic response to immune checkpoint inhibitors, such as microsatellite instability (MSI), and therapeutic targets of molecular targeted therapy, such as human epidermal growth factor receptor 2 (HER-2). Therefore, tumor budding is a major element in the formulation of risk stratification and precision medicine strategies for patients with gastric cancer. |
| first_indexed | 2024-04-10T20:55:38Z |
| format | Article |
| id | doaj.art-73f5633455294b17a97a380558060522 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-10T20:55:38Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-73f5633455294b17a97a3805580605222023-01-23T06:40:00ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011210.3389/fonc.2022.10039591003959Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini reviewChi XueYuwei DuYuegang LiHuimian XuZhi ZhuIn recent years, the role of tumor budding in gastric cancer has received increased attention across a number of disciplines. Several studies have found associations between tumor budding and the prediction of lymph node metastasis in early gastric cancer, prognosis of advanced gastric cancer, predictors of therapeutic response to immune checkpoint inhibitors, such as microsatellite instability (MSI), and therapeutic targets of molecular targeted therapy, such as human epidermal growth factor receptor 2 (HER-2). Therefore, tumor budding is a major element in the formulation of risk stratification and precision medicine strategies for patients with gastric cancer.https://www.frontiersin.org/articles/10.3389/fonc.2022.1003959/fullEMTgastric cancerprognosistumor buddingtherapeutic response |
| spellingShingle | Chi Xue Yuwei Du Yuegang Li Huimian Xu Zhi Zhu Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review Frontiers in Oncology EMT gastric cancer prognosis tumor budding therapeutic response |
| title | Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review |
| title_full | Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review |
| title_fullStr | Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review |
| title_full_unstemmed | Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review |
| title_short | Tumor budding as a predictor for prognosis and therapeutic response in gastric cancer: A mini review |
| title_sort | tumor budding as a predictor for prognosis and therapeutic response in gastric cancer a mini review |
| topic | EMT gastric cancer prognosis tumor budding therapeutic response |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.1003959/full |
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