Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients.

Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients.

To evaluate the mRNA and protein expressions of NLRP3 inflammasome and its downstream inflammatory factors in human dry eye.We recruited 54 patients with Sjögren's syndrome dry eye (SSDE), 50 patients with non-Sjögren's syndrome dry eye (NSSDE), and 46 healthy controls. Tear film breakup t...

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Bibliographic Details
Main Authors: Liangliang Niu, Shujie Zhang, Jihong Wu, Ling Chen, Yan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4427105?pdf=render

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