Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention
Background and Objective: The high ratio of neutrophils to lymphocytes is a predictor of the risk of myocardial infarction in people who have coronary artery angiography. The purpose of this study was to measure this proportion in the assessment of damage through interventions in patients with non-e...
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| Format: | Article |
| Language: | fas |
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Hamadan University of Medical Sciences
2019-03-01
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| Series: | پزشکی بالینی ابن سینا |
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| Online Access: | http://sjh.umsha.ac.ir/article-1-1821-en.html |
| _version_ | 1818458965017624576 |
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| author | Farzad Emami Fatemeh Pakrad Jalal Poorolajal Behshad Naghshtabrizi Hamid Reza Gholalikhani Azam Alizamir |
| author_facet | Farzad Emami Fatemeh Pakrad Jalal Poorolajal Behshad Naghshtabrizi Hamid Reza Gholalikhani Azam Alizamir |
| author_sort | Farzad Emami |
| collection | DOAJ |
| description | Background and Objective: The high ratio of neutrophils to lymphocytes is a predictor of the risk of myocardial infarction in people who have coronary artery angiography. The purpose of this study was to measure this proportion in the assessment of damage through interventions in patients with non-emergency angioplasty.
Materials and Methods: A prospective cohort study was performed on 122 patients referring to Hamadan Farshchian Heart Center, Hamadan, Iran, during 2017 for selected angioplasty. Patients were divided into two groups according to the ratio of neutrophil/ lymphocyte. Data were collected through a checklist and blood test results, including neutrophil/lymphocyte ratio, erythrocyte sedimentation rate (ESR), C-reactive Protein (CRP), Creatine kinase-MB (CKMB), and troponin before angioplasty, as well as 6 and 12 h after angioplasty. The Chi-square test and independent t-test were performed using Stata software (version 14).
Results: There was no significant difference between the ESR levels in the two groups before the angioplasty (P=0.431). However, there were significant differences between the two groups 6 h (P=0.001) and 12 h after the angioplasty (P=0.011). There was no significant difference between the blood level of troponin in both groups before (P=0.310) and 6 h after (P=0.186). However, there was a significant difference between the two groups 12 h after the angioplasty (P=0.042).
Conclusion: The results showed that an increase in the level of troponin elevated neutrophil/lymphocyte ratio and ESR. However, there was no significant difference in CRP and CKMB levels, although there were significant changes in clinical status. |
| first_indexed | 2024-12-14T23:06:50Z |
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| id | doaj.art-73f84246c7d74faf9ccfc9cc9c55daf8 |
| institution | Directory Open Access Journal |
| issn | 2588-722X 2588-7238 |
| language | fas |
| last_indexed | 2024-12-14T23:06:50Z |
| publishDate | 2019-03-01 |
| publisher | Hamadan University of Medical Sciences |
| record_format | Article |
| series | پزشکی بالینی ابن سینا |
| spelling | doaj.art-73f84246c7d74faf9ccfc9cc9c55daf82022-12-21T22:44:18ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382019-03-01254185192Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary InterventionFarzad Emami0Fatemeh Pakrad1Jalal Poorolajal2Behshad Naghshtabrizi3Hamid Reza Gholalikhani4Azam Alizamir5 Background and Objective: The high ratio of neutrophils to lymphocytes is a predictor of the risk of myocardial infarction in people who have coronary artery angiography. The purpose of this study was to measure this proportion in the assessment of damage through interventions in patients with non-emergency angioplasty. Materials and Methods: A prospective cohort study was performed on 122 patients referring to Hamadan Farshchian Heart Center, Hamadan, Iran, during 2017 for selected angioplasty. Patients were divided into two groups according to the ratio of neutrophil/ lymphocyte. Data were collected through a checklist and blood test results, including neutrophil/lymphocyte ratio, erythrocyte sedimentation rate (ESR), C-reactive Protein (CRP), Creatine kinase-MB (CKMB), and troponin before angioplasty, as well as 6 and 12 h after angioplasty. The Chi-square test and independent t-test were performed using Stata software (version 14). Results: There was no significant difference between the ESR levels in the two groups before the angioplasty (P=0.431). However, there were significant differences between the two groups 6 h (P=0.001) and 12 h after the angioplasty (P=0.011). There was no significant difference between the blood level of troponin in both groups before (P=0.310) and 6 h after (P=0.186). However, there was a significant difference between the two groups 12 h after the angioplasty (P=0.042). Conclusion: The results showed that an increase in the level of troponin elevated neutrophil/lymphocyte ratio and ESR. However, there was no significant difference in CRP and CKMB levels, although there were significant changes in clinical status.http://sjh.umsha.ac.ir/article-1-1821-en.htmlangioplastylymphocytemyocardial infarctionneutrophil |
| spellingShingle | Farzad Emami Fatemeh Pakrad Jalal Poorolajal Behshad Naghshtabrizi Hamid Reza Gholalikhani Azam Alizamir Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention پزشکی بالینی ابن سینا angioplasty lymphocyte myocardial infarction neutrophil |
| title | Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention |
| title_full | Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention |
| title_fullStr | Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention |
| title_full_unstemmed | Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention |
| title_short | Relation of Neutrophil to Lymphocyte Ratio with Myocardial Damage in Patients Undergoing Elective Percutaneous Coronary Intervention |
| title_sort | relation of neutrophil to lymphocyte ratio with myocardial damage in patients undergoing elective percutaneous coronary intervention |
| topic | angioplasty lymphocyte myocardial infarction neutrophil |
| url | http://sjh.umsha.ac.ir/article-1-1821-en.html |
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