Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation
BackgroundWith the growing prevalence of atrial fibrillation (AF), concomitant atrial functional tricuspid regurgitation (FTR) is increasing. In this study, we aimed to elucidate the incidence of significant atrial FTR and its association with tricuspid valvular (TV) deformation in patients with per...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1023732/full |
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| author | Yuko Yamamoto Masao Daimon Masao Daimon Koki Nakanishi Tomoko Nakao Tomoko Nakao Megumi Hirokawa Jumpei Ishiwata Hiroyuki Kiriyama Yuriko Yoshida Kentaro Iwama Kazutoshi Hirose Yasuhiro Mukai Norifumi Takeda Yutaka Yatomi Issei Komuro |
| author_facet | Yuko Yamamoto Masao Daimon Masao Daimon Koki Nakanishi Tomoko Nakao Tomoko Nakao Megumi Hirokawa Jumpei Ishiwata Hiroyuki Kiriyama Yuriko Yoshida Kentaro Iwama Kazutoshi Hirose Yasuhiro Mukai Norifumi Takeda Yutaka Yatomi Issei Komuro |
| author_sort | Yuko Yamamoto |
| collection | DOAJ |
| description | BackgroundWith the growing prevalence of atrial fibrillation (AF), concomitant atrial functional tricuspid regurgitation (FTR) is increasing. In this study, we aimed to elucidate the incidence of significant atrial FTR and its association with tricuspid valvular (TV) deformation in patients with persistent AF.MethodsWe retrospectively enrolled 344 patients (73.0 ± 9.3 years, 95 female) with persistent AF who underwent 2-dimensional echocardiography. We excluded patients with left-sided heart disease, pulmonary hypertension treated with pulmonary vasodilators, and congenital heart disease. We defined significant TR as having TR ≥ moderate; and tricuspid annulus (TA) diameter, tethering height, and area were measured in all patients.ResultsAmong the study population, 80 (23.3%) patients had significant TR. TA diameter, tethering height, and area were significantly greater in the significant TR group (all p < 0.001). In multivariable analysis, TA diameter was independently associated with significant TR (odds ratio 1.1 per mm, p = 0.03), whereas TV tethering height was not. Receiver operating characteristic curve for significant TR exhibited the best predictive value of TA diameter indexed for body surface area [23 mm/m2; area under the curve (AUC) = 0.87] compared with absolute TA diameter (39 mm; AUC = 0.74) and TA diameter indexed for height (0.22 mm/cm; AUC = 0.80).ConclusionApproximately 25% of patients with persistent AF had significant TR. The BSA-corrected TA diameter was strongly associated with significant TR, which might be helpful for predicting the development of significant TR and considering its therapeutic strategy in patients with persistent AF. |
| first_indexed | 2024-04-11T05:48:54Z |
| format | Article |
| id | doaj.art-73fa10801ba145a2958c7675922d7887 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-11T05:48:54Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-73fa10801ba145a2958c7675922d78872022-12-22T04:42:08ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-12-01910.3389/fcvm.2022.10237321023732Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillationYuko Yamamoto0Masao Daimon1Masao Daimon2Koki Nakanishi3Tomoko Nakao4Tomoko Nakao5Megumi Hirokawa6Jumpei Ishiwata7Hiroyuki Kiriyama8Yuriko Yoshida9Kentaro Iwama10Kazutoshi Hirose11Yasuhiro Mukai12Norifumi Takeda13Yutaka Yatomi14Issei Komuro15Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, JapanDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, JapanBackgroundWith the growing prevalence of atrial fibrillation (AF), concomitant atrial functional tricuspid regurgitation (FTR) is increasing. In this study, we aimed to elucidate the incidence of significant atrial FTR and its association with tricuspid valvular (TV) deformation in patients with persistent AF.MethodsWe retrospectively enrolled 344 patients (73.0 ± 9.3 years, 95 female) with persistent AF who underwent 2-dimensional echocardiography. We excluded patients with left-sided heart disease, pulmonary hypertension treated with pulmonary vasodilators, and congenital heart disease. We defined significant TR as having TR ≥ moderate; and tricuspid annulus (TA) diameter, tethering height, and area were measured in all patients.ResultsAmong the study population, 80 (23.3%) patients had significant TR. TA diameter, tethering height, and area were significantly greater in the significant TR group (all p < 0.001). In multivariable analysis, TA diameter was independently associated with significant TR (odds ratio 1.1 per mm, p = 0.03), whereas TV tethering height was not. Receiver operating characteristic curve for significant TR exhibited the best predictive value of TA diameter indexed for body surface area [23 mm/m2; area under the curve (AUC) = 0.87] compared with absolute TA diameter (39 mm; AUC = 0.74) and TA diameter indexed for height (0.22 mm/cm; AUC = 0.80).ConclusionApproximately 25% of patients with persistent AF had significant TR. The BSA-corrected TA diameter was strongly associated with significant TR, which might be helpful for predicting the development of significant TR and considering its therapeutic strategy in patients with persistent AF.https://www.frontiersin.org/articles/10.3389/fcvm.2022.1023732/fullatrial fibrillationtethering heighttricuspid annular dilationtricuspid regurgitationvalvular heart disease |
| spellingShingle | Yuko Yamamoto Masao Daimon Masao Daimon Koki Nakanishi Tomoko Nakao Tomoko Nakao Megumi Hirokawa Jumpei Ishiwata Hiroyuki Kiriyama Yuriko Yoshida Kentaro Iwama Kazutoshi Hirose Yasuhiro Mukai Norifumi Takeda Yutaka Yatomi Issei Komuro Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation Frontiers in Cardiovascular Medicine atrial fibrillation tethering height tricuspid annular dilation tricuspid regurgitation valvular heart disease |
| title | Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| title_full | Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| title_fullStr | Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| title_full_unstemmed | Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| title_short | Incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| title_sort | incidence of atrial functional tricuspid regurgitation and its correlation with tricuspid valvular deformation in patients with persistent atrial fibrillation |
| topic | atrial fibrillation tethering height tricuspid annular dilation tricuspid regurgitation valvular heart disease |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1023732/full |
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