The unilateral involution in the thymus of a 96-year-old male leads to the preservation of structural integrity in one thymic lobe, as assessed by the expression of medullar and cortical antigens and the presence of CD3+ cells

The process of thymic involution begins soon after birth and continues through adult life. Although evolutionary conserved in all vertebrates, the thymic involution has no defined kinetics. Little is known about the pace of its regression in humans, except that there is a marked increase of thymic i...

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Bibliographic Details
Main Authors: Pranuthi Kanneganti, Joseph Lyle, Julia H. Smith, Heather McGuire, Richaela Denlinger, Malgorzata Simm
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022030225