Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population

Abstract Background Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the...

Full description

Bibliographic Details
Main Authors: Nicola Principi, Susanna Esposito
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Italian Journal of Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s13052-021-01192-4
_version_ 1798026502118309888
author Nicola Principi
Susanna Esposito
author_facet Nicola Principi
Susanna Esposito
author_sort Nicola Principi
collection DOAJ
description Abstract Background Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the reasons for overcoming hesitancy towards COVID-19 vaccination in children and adolescents and to highlight the importance of universal COVID-19 vaccination in the pediatric population. Main findings Recent epidemiological data suggest that the risk that a child with COVID-19 is hospitalized or admitted to the pediatric intensive care unit is greater than initially thought. Children may also suffer from long COVID and school closure because of COVID-19 can cause relevant mental health problems in the pediatric population. Placebo-controlled, observer-blinded, clinical trials showed appropriate efficacy, safety and tolerability of authorized mRNA COVID-19 vaccines in children and adolescents 12–17 years old. Vaccination in children younger than 12 years of age will allow further benefits . Conclusions COVID-19 vaccine administration seems mandatory in all the children and adolescents because of COVID-19 related complications as well as the efficacy, safety and tolerability of COVID-19 vaccines in this population. Due to the recent approval of COVID-9 vaccines for children 5–10 years old, it is desirable that vaccine opponents can understand how important is the universal immunization against COVID-19 for the pediatric subjects.
first_indexed 2024-04-11T18:36:27Z
format Article
id doaj.art-73fc86de6562405cb71c5ed8d0a1e1bf
institution Directory Open Access Journal
issn 1824-7288
language English
last_indexed 2024-04-11T18:36:27Z
publishDate 2022-01-01
publisher BMC
record_format Article
series Italian Journal of Pediatrics
spelling doaj.art-73fc86de6562405cb71c5ed8d0a1e1bf2022-12-22T04:09:15ZengBMCItalian Journal of Pediatrics1824-72882022-01-014811510.1186/s13052-021-01192-4Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric populationNicola Principi0Susanna Esposito1Università degli Studi di MilanoPietro Barilla Children’s Hospital, Department of Medicine and Surgery, University of ParmaAbstract Background Despite the growing evidence of the extreme efficacy of COVID-19 vaccines in adults and the elderly, the administration of the same prophylactic measures to pediatric subjects is debated by some parents and by a number of researchers. The aim of this manuscript is to explain the reasons for overcoming hesitancy towards COVID-19 vaccination in children and adolescents and to highlight the importance of universal COVID-19 vaccination in the pediatric population. Main findings Recent epidemiological data suggest that the risk that a child with COVID-19 is hospitalized or admitted to the pediatric intensive care unit is greater than initially thought. Children may also suffer from long COVID and school closure because of COVID-19 can cause relevant mental health problems in the pediatric population. Placebo-controlled, observer-blinded, clinical trials showed appropriate efficacy, safety and tolerability of authorized mRNA COVID-19 vaccines in children and adolescents 12–17 years old. Vaccination in children younger than 12 years of age will allow further benefits . Conclusions COVID-19 vaccine administration seems mandatory in all the children and adolescents because of COVID-19 related complications as well as the efficacy, safety and tolerability of COVID-19 vaccines in this population. Due to the recent approval of COVID-9 vaccines for children 5–10 years old, it is desirable that vaccine opponents can understand how important is the universal immunization against COVID-19 for the pediatric subjects.https://doi.org/10.1186/s13052-021-01192-4COVID-19COVID-19 vaccinePediatric infectious diseaseSARS-CoV-2
spellingShingle Nicola Principi
Susanna Esposito
Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
Italian Journal of Pediatrics
COVID-19
COVID-19 vaccine
Pediatric infectious disease
SARS-CoV-2
title Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_full Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_fullStr Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_full_unstemmed Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_short Reasons in favour of universal vaccination campaign against COVID-19 in the pediatric population
title_sort reasons in favour of universal vaccination campaign against covid 19 in the pediatric population
topic COVID-19
COVID-19 vaccine
Pediatric infectious disease
SARS-CoV-2
url https://doi.org/10.1186/s13052-021-01192-4
work_keys_str_mv AT nicolaprincipi reasonsinfavourofuniversalvaccinationcampaignagainstcovid19inthepediatricpopulation
AT susannaesposito reasonsinfavourofuniversalvaccinationcampaignagainstcovid19inthepediatricpopulation