Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus

Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against...

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Main Authors: Indira Dwi Aulia, Sari Edi Cahyaningrum
Format: Article
Language:English
Published: University of Mataram 2023-07-01
Series:Jurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam)
Subjects:
Online Access:https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994
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author Indira Dwi Aulia
Sari Edi Cahyaningrum
author_facet Indira Dwi Aulia
Sari Edi Cahyaningrum
author_sort Indira Dwi Aulia
collection DOAJ
description Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm.
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spelling doaj.art-7407b7cdcf354b0e8c38afc80dc99a012023-08-28T02:13:26ZengUniversity of MataramJurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam)1907-17442460-15002023-07-0118465065810.29303/jpm.v18i4.49945713Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureusIndira Dwi Aulia0Sari Edi Cahyaningrum1Chemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri SurabayaChemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri SurabayaBinahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm.https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial
spellingShingle Indira Dwi Aulia
Sari Edi Cahyaningrum
Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
Jurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam)
binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial
title Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
title_full Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
title_fullStr Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
title_full_unstemmed Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
title_short Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
title_sort characterization and antibacterial activity test of chitosan silver nanoparticle gel and binahong leaf extract anredera cordifolia tenore steen against staphylococcus aureus
topic binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial
url https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994
work_keys_str_mv AT indiradwiaulia characterizationandantibacterialactivitytestofchitosansilvernanoparticlegelandbinahongleafextractanrederacordifoliatenoresteenagainststaphylococcusaureus
AT sariedicahyaningrum characterizationandantibacterialactivitytestofchitosansilvernanoparticlegelandbinahongleafextractanrederacordifoliatenoresteenagainststaphylococcusaureus