Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus
Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against...
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Format: | Article |
Language: | English |
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University of Mataram
2023-07-01
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Series: | Jurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam) |
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Online Access: | https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994 |
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author | Indira Dwi Aulia Sari Edi Cahyaningrum |
author_facet | Indira Dwi Aulia Sari Edi Cahyaningrum |
author_sort | Indira Dwi Aulia |
collection | DOAJ |
description | Binahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm. |
first_indexed | 2024-03-12T13:11:19Z |
format | Article |
id | doaj.art-7407b7cdcf354b0e8c38afc80dc99a01 |
institution | Directory Open Access Journal |
issn | 1907-1744 2460-1500 |
language | English |
last_indexed | 2024-03-12T13:11:19Z |
publishDate | 2023-07-01 |
publisher | University of Mataram |
record_format | Article |
series | Jurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam) |
spelling | doaj.art-7407b7cdcf354b0e8c38afc80dc99a012023-08-28T02:13:26ZengUniversity of MataramJurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam)1907-17442460-15002023-07-0118465065810.29303/jpm.v18i4.49945713Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureusIndira Dwi Aulia0Sari Edi Cahyaningrum1Chemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri SurabayaChemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri SurabayaBinahong leaf is one of the medical plants that contain alkaloids, saponins, and flavonoids, which directly act as antibiotics. Additionally, chitosan and silver nanoparticles also possess antibacterial properties. This study aims to determine the antibacterial activity of a gel preparation against Staphylococcus aureus bacteria. It was a true experimental study with data collection carried out at the inorganic level. This study's results show that the gel preparation's organoleptic test meets the requirements for skin pH of 4.5-6.5. The spreading test meets the need for good distribution on the skin, which is 5-7cm. The antibacterial activity test showed that the largest diameter of the inhibition zone was observed at concentration F5 (5% binahong leaf extract), which was 13.4 mm.https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial |
spellingShingle | Indira Dwi Aulia Sari Edi Cahyaningrum Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus Jurnal Pijar MIPA (Pengkajian Ilmu dan Pengajaran Matematika dan Ilmu Pengetahuan Alam) binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial |
title | Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus |
title_full | Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus |
title_fullStr | Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus |
title_full_unstemmed | Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus |
title_short | Characterization and antibacterial activity test of chitosan-silver nanoparticle gel and binahong leaf extract (Anredera cordifolia (Tenore) Steen) against Staphylococcus aureus |
title_sort | characterization and antibacterial activity test of chitosan silver nanoparticle gel and binahong leaf extract anredera cordifolia tenore steen against staphylococcus aureus |
topic | binahong leaf (anredera cordifolia (tenore) steen), chitosan, silver nanoparticles, staphylococcus aureus, ggel, antibacterial |
url | https://jurnalfkip.unram.ac.id/index.php/JPM/article/view/4994 |
work_keys_str_mv | AT indiradwiaulia characterizationandantibacterialactivitytestofchitosansilvernanoparticlegelandbinahongleafextractanrederacordifoliatenoresteenagainststaphylococcusaureus AT sariedicahyaningrum characterizationandantibacterialactivitytestofchitosansilvernanoparticlegelandbinahongleafextractanrederacordifoliatenoresteenagainststaphylococcusaureus |