The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases
Pseudomonas aeruginosa is a widespread multidrug-resistant opportunistic human pathogen with an extremely high mortality rate that leads to urinary tract infection morbidities in particular. Variability and dynamics in genome features and ecological flexibility help these bacteria adapt to many envi...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340923007795 |
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| author | L.R. Valeeva D.S. Pudova N.N. Khabipova L.H. Shigapova E.I. Shagimardanova A.M. Rogov T.R. Tagirova Z.G. Gimadeev M.R. Sharipova |
| author_facet | L.R. Valeeva D.S. Pudova N.N. Khabipova L.H. Shigapova E.I. Shagimardanova A.M. Rogov T.R. Tagirova Z.G. Gimadeev M.R. Sharipova |
| author_sort | L.R. Valeeva |
| collection | DOAJ |
| description | Pseudomonas aeruginosa is a widespread multidrug-resistant opportunistic human pathogen with an extremely high mortality rate that leads to urinary tract infection morbidities in particular. Variability and dynamics in genome features and ecological flexibility help these bacteria adapt to many environments and hosts and underlie their broad antibiotic resistance. Overall, studies aimed at obtaining a deeper understanding of the genome organization of UTI-associated P. aeruginosa strains are of high importance for sustainable health care worldwide. Herein, we report the draft assembly of entire genomes of two P. aeruginosa strains, PA18 and PA23, isolated from voided urine of patients with urinary tract diseases (hydronephrosis and urolithiasis, respectively) and determine the most important genetic features for pathogenesis and virulence. Whole-genome sequencing and annotation of genomes revealed high similarity between the two UTI strains along with differences in comparison with other uropathogenic P. aeruginosa and reference strains. The 6 981 635 bp and 6 948 153 bp draft genome sequences with GC contents of 65.9% and 65.8%, respectively, provide new insights into the virulence genetic factors and genes associated with antimicrobial resistance. The whole genome data of PA18 and PA23 have been deposited in the NCBI GenBank database (accession numbers JAQRBF000000000.1 and JAQRBG000000000.1, respectively). |
| first_indexed | 2024-03-09T09:22:11Z |
| format | Article |
| id | doaj.art-74081939a7b7483182fa9f31e479427c |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-03-09T09:22:11Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-74081939a7b7483182fa9f31e479427c2023-12-02T07:00:07ZengElsevierData in Brief2352-34092023-12-0151109704The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseasesL.R. Valeeva0D.S. Pudova1N.N. Khabipova2L.H. Shigapova3E.I. Shagimardanova4A.M. Rogov5T.R. Tagirova6Z.G. Gimadeev7M.R. Sharipova8Laboratory of Agrobioengineering, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Parizhskoy Kommuny Str., 9, Kazan 420021, Russia; Corresponding author.Laboratory of Agrobioengineering, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Parizhskoy Kommuny Str., 9, Kazan 420021, RussiaLaboratory of Agrobioengineering, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Parizhskoy Kommuny Str., 9, Kazan 420021, Russia‘Regulatory genomics’ Research Center, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Volkova Str. 18, Kazan 420012, Russia‘Regulatory genomics’ Research Center, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Volkova Str. 18, Kazan 420012, RussiaThe Interdisciplinary Center “Analytical Microscopy”, Kazan (Volga Region) Federal University, Kazan (Volga Region) Federal University, Parizhskoy Kommuny Str., 9, Kazan 420021, RussiaThe Laboratory of clinical bacteriology, the Republican Clinical Hospital of the Republic of Tatarstan, Orenburgskiy trakt, 138, Kazan, 420064, RussiaThe Urological Department of the University Clinic in Kazan, Chekhova Str., 43, Kazan, 420043, RussiaLaboratory of Agrobioengineering, Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, Parizhskoy Kommuny Str., 9, Kazan 420021, RussiaPseudomonas aeruginosa is a widespread multidrug-resistant opportunistic human pathogen with an extremely high mortality rate that leads to urinary tract infection morbidities in particular. Variability and dynamics in genome features and ecological flexibility help these bacteria adapt to many environments and hosts and underlie their broad antibiotic resistance. Overall, studies aimed at obtaining a deeper understanding of the genome organization of UTI-associated P. aeruginosa strains are of high importance for sustainable health care worldwide. Herein, we report the draft assembly of entire genomes of two P. aeruginosa strains, PA18 and PA23, isolated from voided urine of patients with urinary tract diseases (hydronephrosis and urolithiasis, respectively) and determine the most important genetic features for pathogenesis and virulence. Whole-genome sequencing and annotation of genomes revealed high similarity between the two UTI strains along with differences in comparison with other uropathogenic P. aeruginosa and reference strains. The 6 981 635 bp and 6 948 153 bp draft genome sequences with GC contents of 65.9% and 65.8%, respectively, provide new insights into the virulence genetic factors and genes associated with antimicrobial resistance. The whole genome data of PA18 and PA23 have been deposited in the NCBI GenBank database (accession numbers JAQRBF000000000.1 and JAQRBG000000000.1, respectively).http://www.sciencedirect.com/science/article/pii/S2352340923007795Pseudomonas aeruginosaUropathogenDraft genome annotationVirulence factorsAntimicrobial resistance |
| spellingShingle | L.R. Valeeva D.S. Pudova N.N. Khabipova L.H. Shigapova E.I. Shagimardanova A.M. Rogov T.R. Tagirova Z.G. Gimadeev M.R. Sharipova The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases Data in Brief Pseudomonas aeruginosa Uropathogen Draft genome annotation Virulence factors Antimicrobial resistance |
| title | The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| title_full | The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| title_fullStr | The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| title_full_unstemmed | The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| title_short | The dataset on the draft whole-genome sequences of two Pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| title_sort | dataset on the draft whole genome sequences of two pseudomonas aeruginosa strains isolated from urine samples of patients with urinary tract diseases |
| topic | Pseudomonas aeruginosa Uropathogen Draft genome annotation Virulence factors Antimicrobial resistance |
| url | http://www.sciencedirect.com/science/article/pii/S2352340923007795 |
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