Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study
Populations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present...
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| Format: | Article |
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MDPI AG
2022-05-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/5/620 |
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| author | Magdalena Kobus Elżbieta Żądzińska Aneta Sitek Jacek Pełka Jacek J. Rożniecki Bogusław Antoszewski |
| author_facet | Magdalena Kobus Elżbieta Żądzińska Aneta Sitek Jacek Pełka Jacek J. Rożniecki Bogusław Antoszewski |
| author_sort | Magdalena Kobus |
| collection | DOAJ |
| description | Populations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present that light skin may modify the risk of Alzheimer’s and Parkinson’s diseases. However, the relationship between migraine and skin pigmentation has not been investigated yet. The objective of this study is to provide evidence of the relationship between skin pigmentation and migraine prevalence in adults. We examined a group of 148 adults (33 men, 115 women) with migraine and a control group of 107 adults (43 men, 64 women). Parameters of skin pigmentation (melanin index, erythema index, CIElab, and RGB scales) were measured using a DSM II Cortex Technology dermospectrophotometer. Risk of migraine in lightly pigmented adults was elevated. Individuals with a low melanin index had over 3-fold increased risk of migraine (women: OR 3.53, men: OR 3.73). Fair phototype, which results from lightly pigmented skin, was associated with migraine prevalence. Migraineurs should take extra care to protect their skin from the negative effects of solar radiation. |
| first_indexed | 2024-03-10T03:14:35Z |
| format | Article |
| id | doaj.art-740a7fc64e6345179ab38893f4132ac4 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T03:14:35Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-740a7fc64e6345179ab38893f4132ac42023-11-23T10:18:00ZengMDPI AGBrain Sciences2076-34252022-05-0112562010.3390/brainsci12050620Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control StudyMagdalena Kobus0Elżbieta Żądzińska1Aneta Sitek2Jacek Pełka3Jacek J. Rożniecki4Bogusław Antoszewski5Department of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, PolandDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, PolandDepartment of Anthropology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, PolandDepartment of Neurology, Norbert Barlicki Memory University Teaching Hospital, 90-153 Lodz, PolandDepartment of Neurology, Stroke and Neurorehabilitation, Medical University of Lodz, 90-153 Lodz, PolandDepartment of Plastic, Reconstructive and Aesthetic Surgery, Institute of Surgery, Medical University of Lodz, 90-153 Lodz, PolandPopulations with a relatively low concentration of melanin, e.g., inhabitants of Europe, North America, and Australia, are the most vulnerable to the harmful effects of UV radiation. Individuals with fair phototype are at greatest risk of developing skin cancer. Several neurological studies present that light skin may modify the risk of Alzheimer’s and Parkinson’s diseases. However, the relationship between migraine and skin pigmentation has not been investigated yet. The objective of this study is to provide evidence of the relationship between skin pigmentation and migraine prevalence in adults. We examined a group of 148 adults (33 men, 115 women) with migraine and a control group of 107 adults (43 men, 64 women). Parameters of skin pigmentation (melanin index, erythema index, CIElab, and RGB scales) were measured using a DSM II Cortex Technology dermospectrophotometer. Risk of migraine in lightly pigmented adults was elevated. Individuals with a low melanin index had over 3-fold increased risk of migraine (women: OR 3.53, men: OR 3.73). Fair phototype, which results from lightly pigmented skin, was associated with migraine prevalence. Migraineurs should take extra care to protect their skin from the negative effects of solar radiation.https://www.mdpi.com/2076-3425/12/5/620migrainemelaninheadacheskin pigmentationcutaneous colorimetry |
| spellingShingle | Magdalena Kobus Elżbieta Żądzińska Aneta Sitek Jacek Pełka Jacek J. Rożniecki Bogusław Antoszewski Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study Brain Sciences migraine melanin headache skin pigmentation cutaneous colorimetry |
| title | Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study |
| title_full | Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study |
| title_fullStr | Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study |
| title_full_unstemmed | Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study |
| title_short | Risk of Migraine in Europeans with Low Melanin Levels—A Population Based Case-Control Study |
| title_sort | risk of migraine in europeans with low melanin levels a population based case control study |
| topic | migraine melanin headache skin pigmentation cutaneous colorimetry |
| url | https://www.mdpi.com/2076-3425/12/5/620 |
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