Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series
Abdelrahman M Elhusseiny,1,2,* Mohamed M Khodeiry,3,4,* Richard K Lee,4 Tarek Shaarawy,5 Salman Waqar,6 Mohamed S Sayed6 1Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Department of Ophthalmolo...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-07-01
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| Series: | Clinical Ophthalmology |
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| Online Access: | https://www.dovepress.com/early-experience-with-the-paul-glaucoma-implant-in-childhood-glaucoma--peer-reviewed-fulltext-article-OPTH |
| _version_ | 1797785585463590912 |
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| author | Elhusseiny AM Khodeiry MM Lee RK Shaarawy T Waqar S Sayed MS |
| author_facet | Elhusseiny AM Khodeiry MM Lee RK Shaarawy T Waqar S Sayed MS |
| author_sort | Elhusseiny AM |
| collection | DOAJ |
| description | Abdelrahman M Elhusseiny,1,2,* Mohamed M Khodeiry,3,4,* Richard K Lee,4 Tarek Shaarawy,5 Salman Waqar,6 Mohamed S Sayed6 1Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Department of Ophthalmology, Boston Children’s Hospital, Boston, MA, USA; 3Department of Ophthalmology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA; 4Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 5Department of Ophthalmology, Hôpitaux Universitaires de Genève, University of Geneva, Geneva, Switzerland; 6Glaucoma Division, Moorfields Eye Hospitals, Dubai, United Arab Emirates*These authors contributed equally to this workCorrespondence: Mohamed S Sayed, Glaucoma Division, Moorfields Eye Hospitals, Dubai, United Arab Emirates, Tel +97144297888, Email msayed82@hotmail.comPurpose: The Paul glaucoma implant (PGI, Advanced Ophthalmic Innovations, Singapore, Republic of Singapore) is a recently developed novel non-valved glaucoma drainage device (GDD) designed to effectively reduce the intraocular pressure (IOP) in glaucoma patients with a theoretically reduced risk of postoperative complications such as hypotony, endothelial cell loss, strabismus, and diplopia. Limited literature has evaluated its use in adult glaucoma; however, its use in pediatric glaucoma has not been reported to date. We present our early experience with PGI in refractory childhood glaucoma.Patients and Methods: This study was retrospective single-surgeon case series in a single tertiary center.Results: Three eyes of 3 patients with childhood glaucoma were enrolled in the study. During nine months of follow-up, postoperative IOP and number of glaucoma medications were significantly lower than preoperative values in all the enrolled patients. None of the patients developed postoperative complications including postoperative hypotony, choroidal detachment, endophthalmitis, or corneal decompensation.Conclusion: PGI is an efficient and relatively safe surgical treatment option in patients with refractory childhood glaucoma. Further studies with larger number of participants and longer follow-up period are required to confirm our encouraging results.Keywords: glaucoma, pediatric, intraocular pressure, tube, Paul glaucoma implant |
| first_indexed | 2024-03-13T00:56:06Z |
| format | Article |
| id | doaj.art-740c314d767445d6b6f58dea00cfbed1 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-03-13T00:56:06Z |
| publishDate | 2023-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-740c314d767445d6b6f58dea00cfbed12023-07-06T19:09:58ZengDove Medical PressClinical Ophthalmology1177-54832023-07-01Volume 171939194484966Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case SeriesElhusseiny AMKhodeiry MMLee RKShaarawy TWaqar SSayed MSAbdelrahman M Elhusseiny,1,2,* Mohamed M Khodeiry,3,4,* Richard K Lee,4 Tarek Shaarawy,5 Salman Waqar,6 Mohamed S Sayed6 1Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Department of Ophthalmology, Boston Children’s Hospital, Boston, MA, USA; 3Department of Ophthalmology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA; 4Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; 5Department of Ophthalmology, Hôpitaux Universitaires de Genève, University of Geneva, Geneva, Switzerland; 6Glaucoma Division, Moorfields Eye Hospitals, Dubai, United Arab Emirates*These authors contributed equally to this workCorrespondence: Mohamed S Sayed, Glaucoma Division, Moorfields Eye Hospitals, Dubai, United Arab Emirates, Tel +97144297888, Email msayed82@hotmail.comPurpose: The Paul glaucoma implant (PGI, Advanced Ophthalmic Innovations, Singapore, Republic of Singapore) is a recently developed novel non-valved glaucoma drainage device (GDD) designed to effectively reduce the intraocular pressure (IOP) in glaucoma patients with a theoretically reduced risk of postoperative complications such as hypotony, endothelial cell loss, strabismus, and diplopia. Limited literature has evaluated its use in adult glaucoma; however, its use in pediatric glaucoma has not been reported to date. We present our early experience with PGI in refractory childhood glaucoma.Patients and Methods: This study was retrospective single-surgeon case series in a single tertiary center.Results: Three eyes of 3 patients with childhood glaucoma were enrolled in the study. During nine months of follow-up, postoperative IOP and number of glaucoma medications were significantly lower than preoperative values in all the enrolled patients. None of the patients developed postoperative complications including postoperative hypotony, choroidal detachment, endophthalmitis, or corneal decompensation.Conclusion: PGI is an efficient and relatively safe surgical treatment option in patients with refractory childhood glaucoma. Further studies with larger number of participants and longer follow-up period are required to confirm our encouraging results.Keywords: glaucoma, pediatric, intraocular pressure, tube, Paul glaucoma implanthttps://www.dovepress.com/early-experience-with-the-paul-glaucoma-implant-in-childhood-glaucoma--peer-reviewed-fulltext-article-OPTHglaucomapediatricintraocular pressuretubepaul glaucoma implant |
| spellingShingle | Elhusseiny AM Khodeiry MM Lee RK Shaarawy T Waqar S Sayed MS Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series Clinical Ophthalmology glaucoma pediatric intraocular pressure tube paul glaucoma implant |
| title | Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series |
| title_full | Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series |
| title_fullStr | Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series |
| title_full_unstemmed | Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series |
| title_short | Early Experience with the Paul Glaucoma Implant in Childhood Glaucoma: A Case Series |
| title_sort | early experience with the paul glaucoma implant in childhood glaucoma a case series |
| topic | glaucoma pediatric intraocular pressure tube paul glaucoma implant |
| url | https://www.dovepress.com/early-experience-with-the-paul-glaucoma-implant-in-childhood-glaucoma--peer-reviewed-fulltext-article-OPTH |
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