Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich

This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This is illu...

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Main Authors: Konstantin Barylyuk, Vladimir Frankevich, Alfredo J. Ibáñez, Pablo Martinez-Lozano Sinues, Renato Zenobi
Format: Article
Language:deu
Published: Swiss Chemical Society 2014-03-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/5521
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author Konstantin Barylyuk
Vladimir Frankevich
Alfredo J. Ibáñez
Pablo Martinez-Lozano Sinues
Renato Zenobi
author_facet Konstantin Barylyuk
Vladimir Frankevich
Alfredo J. Ibáñez
Pablo Martinez-Lozano Sinues
Renato Zenobi
author_sort Konstantin Barylyuk
collection DOAJ
description This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This is illustrated with examples from the mass spectrometric study of noncovalent interactions, using both native ESI and MALDI for ionization, the investigation of the gas-phase conformation of ionized bio-macromolecules, the use of ambient mass spectrometry for rapid, on-line analyses of, for example, exhaled breath, and the use of MALDI and microarray technologies for studying metabolites with extreme sensitivity, sufficient to probe the metabolites from single cells.
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spelling doaj.art-741346d897e04fd3b527d051e44afb1d2022-12-21T17:24:43ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242014-03-0168310.2533/chimia.2014.119Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH ZurichKonstantin BarylyukVladimir FrankevichAlfredo J. IbáñezPablo Martinez-Lozano SinuesRenato Zenobi0Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This is illustrated with examples from the mass spectrometric study of noncovalent interactions, using both native ESI and MALDI for ionization, the investigation of the gas-phase conformation of ionized bio-macromolecules, the use of ambient mass spectrometry for rapid, on-line analyses of, for example, exhaled breath, and the use of MALDI and microarray technologies for studying metabolites with extreme sensitivity, sufficient to probe the metabolites from single cells. https://www.chimia.ch/chimia/article/view/5521Ambient mass spectrometryEsi mass spectrometryMaldi mass spectrometryNoncovalent interactionsSingle-cell metabolomics
spellingShingle Konstantin Barylyuk
Vladimir Frankevich
Alfredo J. Ibáñez
Pablo Martinez-Lozano Sinues
Renato Zenobi
Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
CHIMIA
Ambient mass spectrometry
Esi mass spectrometry
Maldi mass spectrometry
Noncovalent interactions
Single-cell metabolomics
title Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
title_full Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
title_fullStr Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
title_full_unstemmed Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
title_short Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
title_sort mass spectrometry research at the laboratory for organic chemistry eth zurich
topic Ambient mass spectrometry
Esi mass spectrometry
Maldi mass spectrometry
Noncovalent interactions
Single-cell metabolomics
url https://www.chimia.ch/chimia/article/view/5521
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AT alfredojibanez massspectrometryresearchatthelaboratoryfororganicchemistryethzurich
AT pablomartinezlozanosinues massspectrometryresearchatthelaboratoryfororganicchemistryethzurich
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