Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This is illu...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | deu |
Published: |
Swiss Chemical Society
2014-03-01
|
Series: | CHIMIA |
Subjects: | |
Online Access: | https://www.chimia.ch/chimia/article/view/5521 |
_version_ | 1819278680580423680 |
---|---|
author | Konstantin Barylyuk Vladimir Frankevich Alfredo J. Ibáñez Pablo Martinez-Lozano Sinues Renato Zenobi |
author_facet | Konstantin Barylyuk Vladimir Frankevich Alfredo J. Ibáñez Pablo Martinez-Lozano Sinues Renato Zenobi |
author_sort | Konstantin Barylyuk |
collection | DOAJ |
description |
This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This
is illustrated with examples from the mass spectrometric study of noncovalent interactions, using both native ESI and MALDI for ionization, the investigation of the gas-phase conformation of ionized bio-macromolecules, the use of ambient mass spectrometry for rapid, on-line analyses of, for
example, exhaled breath, and the use of MALDI and microarray technologies for studying metabolites with extreme sensitivity, sufficient to probe the metabolites from single cells.
|
first_indexed | 2024-12-24T00:15:52Z |
format | Article |
id | doaj.art-741346d897e04fd3b527d051e44afb1d |
institution | Directory Open Access Journal |
issn | 0009-4293 2673-2424 |
language | deu |
last_indexed | 2024-12-24T00:15:52Z |
publishDate | 2014-03-01 |
publisher | Swiss Chemical Society |
record_format | Article |
series | CHIMIA |
spelling | doaj.art-741346d897e04fd3b527d051e44afb1d2022-12-21T17:24:43ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242014-03-0168310.2533/chimia.2014.119Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH ZurichKonstantin BarylyukVladimir FrankevichAlfredo J. IbáñezPablo Martinez-Lozano SinuesRenato Zenobi0Department of Chemistry and Applied Biosciences, ETH Zurich, CH-8093 Zurich, Switzerland This contribution covers the most important activities of the Zenobi research group at the Organic Chemistry Laboratory, ETH Zurich. We work in a number of interrelated areas that encompass fundamental/mechanistic research, instrument and methods development, and applications. This is illustrated with examples from the mass spectrometric study of noncovalent interactions, using both native ESI and MALDI for ionization, the investigation of the gas-phase conformation of ionized bio-macromolecules, the use of ambient mass spectrometry for rapid, on-line analyses of, for example, exhaled breath, and the use of MALDI and microarray technologies for studying metabolites with extreme sensitivity, sufficient to probe the metabolites from single cells. https://www.chimia.ch/chimia/article/view/5521Ambient mass spectrometryEsi mass spectrometryMaldi mass spectrometryNoncovalent interactionsSingle-cell metabolomics |
spellingShingle | Konstantin Barylyuk Vladimir Frankevich Alfredo J. Ibáñez Pablo Martinez-Lozano Sinues Renato Zenobi Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich CHIMIA Ambient mass spectrometry Esi mass spectrometry Maldi mass spectrometry Noncovalent interactions Single-cell metabolomics |
title | Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich |
title_full | Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich |
title_fullStr | Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich |
title_full_unstemmed | Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich |
title_short | Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich |
title_sort | mass spectrometry research at the laboratory for organic chemistry eth zurich |
topic | Ambient mass spectrometry Esi mass spectrometry Maldi mass spectrometry Noncovalent interactions Single-cell metabolomics |
url | https://www.chimia.ch/chimia/article/view/5521 |
work_keys_str_mv | AT konstantinbarylyuk massspectrometryresearchatthelaboratoryfororganicchemistryethzurich AT vladimirfrankevich massspectrometryresearchatthelaboratoryfororganicchemistryethzurich AT alfredojibanez massspectrometryresearchatthelaboratoryfororganicchemistryethzurich AT pablomartinezlozanosinues massspectrometryresearchatthelaboratoryfororganicchemistryethzurich AT renatozenobi massspectrometryresearchatthelaboratoryfororganicchemistryethzurich |