Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study
The purpose of this study was to identify subgroups of quality of life (QOL) changes in breast cancer survivors (BCSs), and to determine factors associated with subgroups of consistently low or deteriorated QOL. We enrolled 101 women recently diagnosed with breast cancer in South Korea and asked the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/24/5809 |
| _version_ | 1797381669777309696 |
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| author | Soo-Hyun Kim Ha-Yeon Jo |
| author_facet | Soo-Hyun Kim Ha-Yeon Jo |
| author_sort | Soo-Hyun Kim |
| collection | DOAJ |
| description | The purpose of this study was to identify subgroups of quality of life (QOL) changes in breast cancer survivors (BCSs), and to determine factors associated with subgroups of consistently low or deteriorated QOL. We enrolled 101 women recently diagnosed with breast cancer in South Korea and asked them to complete a questionnaire at baseline (within 1 month of diagnosis), 1 year later (Year 1), 2 years later (Year 2), and 3 years later (Year 3). We assessed QOL using the global QOL subscale from the EORTC QLQ-C30. We defined low QOL as a global QOL score 10 points below the mean score of the general population. Based on low QOL as defined in this study, we identified subgroups of QOL changes over 3 years. We identified four subgroups of QOL changes: improved (47.4%), stable (30%), continuously low (8.8%), and deteriorated (13.8%), and considered the last two categories (22.6%) poor QOL. Logistic regression analyses demonstrated that significant determinants of poor QOL were insomnia at Year 1, fatigue and anxiety at Year 2, and fatigue, depression, and comorbidity at Year 3. In conclusion, persistent symptoms of insomnia, fatigue, anxiety, depression, and comorbidity are potential risk factors for poor QOL in BCSs. |
| first_indexed | 2024-03-08T20:55:47Z |
| format | Article |
| id | doaj.art-7415bcac0fc346699b8581b1e04df786 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-08T20:55:47Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-7415bcac0fc346699b8581b1e04df7862023-12-22T13:58:56ZengMDPI AGCancers2072-66942023-12-011524580910.3390/cancers15245809Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up StudySoo-Hyun Kim0Ha-Yeon Jo1Department of Nursing, Inha University, Incheon 22212, Republic of KoreaDepartment of Nursing, Inha University, Incheon 22212, Republic of KoreaThe purpose of this study was to identify subgroups of quality of life (QOL) changes in breast cancer survivors (BCSs), and to determine factors associated with subgroups of consistently low or deteriorated QOL. We enrolled 101 women recently diagnosed with breast cancer in South Korea and asked them to complete a questionnaire at baseline (within 1 month of diagnosis), 1 year later (Year 1), 2 years later (Year 2), and 3 years later (Year 3). We assessed QOL using the global QOL subscale from the EORTC QLQ-C30. We defined low QOL as a global QOL score 10 points below the mean score of the general population. Based on low QOL as defined in this study, we identified subgroups of QOL changes over 3 years. We identified four subgroups of QOL changes: improved (47.4%), stable (30%), continuously low (8.8%), and deteriorated (13.8%), and considered the last two categories (22.6%) poor QOL. Logistic regression analyses demonstrated that significant determinants of poor QOL were insomnia at Year 1, fatigue and anxiety at Year 2, and fatigue, depression, and comorbidity at Year 3. In conclusion, persistent symptoms of insomnia, fatigue, anxiety, depression, and comorbidity are potential risk factors for poor QOL in BCSs.https://www.mdpi.com/2072-6694/15/24/5809breast cancerdepressionfatigueinsomniaquality of life |
| spellingShingle | Soo-Hyun Kim Ha-Yeon Jo Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study Cancers breast cancer depression fatigue insomnia quality of life |
| title | Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study |
| title_full | Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study |
| title_fullStr | Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study |
| title_full_unstemmed | Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study |
| title_short | Factors Associated with Poor Quality of Life in Breast Cancer Survivors: A 3-Year Follow-Up Study |
| title_sort | factors associated with poor quality of life in breast cancer survivors a 3 year follow up study |
| topic | breast cancer depression fatigue insomnia quality of life |
| url | https://www.mdpi.com/2072-6694/15/24/5809 |
| work_keys_str_mv | AT soohyunkim factorsassociatedwithpoorqualityoflifeinbreastcancersurvivorsa3yearfollowupstudy AT hayeonjo factorsassociatedwithpoorqualityoflifeinbreastcancersurvivorsa3yearfollowupstudy |