Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation.

Research on neutrophil biology has been limited by the short life span and limited genetic manipulability of these cells, driving the need for representative and efficient model cell lines. The promyelocytic cell line HL-60 and its subline PLB-985 can be differentiated into neutrophil-like cells (NL...

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Príomhchruthaitheoirí: Suhani B Bhakta, Stefan M Lundgren, Bethany N Sesti, Barbara A Flores, Emel Akdogan, Sean R Collins, Frances Mercer
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2024-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297758&type=printable