Neutrophil-like cells derived from the HL-60 cell-line as a genetically-tractable model for neutrophil degranulation.

Research on neutrophil biology has been limited by the short life span and limited genetic manipulability of these cells, driving the need for representative and efficient model cell lines. The promyelocytic cell line HL-60 and its subline PLB-985 can be differentiated into neutrophil-like cells (NL...

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Main Authors: Suhani B Bhakta, Stefan M Lundgren, Bethany N Sesti, Barbara A Flores, Emel Akdogan, Sean R Collins, Frances Mercer
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2024-01-01
叢編:PLoS ONE
在線閱讀:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0297758&type=printable