Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation

Purpose. To report a case of postoperative endophthalmitis after combined cataract extraction and iStent inject implantation. Observation. A 70-year-old male with a nuclear sclerotic cataract and primary open-angle glaucoma underwent an uneventful phacoemulsification cataract extraction with implant...

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Main Authors: Johnson Huang, Minh T. Nguyen, Mai Tsukikawa, Andrew Chen
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2023/3132866
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author Johnson Huang
Minh T. Nguyen
Mai Tsukikawa
Andrew Chen
author_facet Johnson Huang
Minh T. Nguyen
Mai Tsukikawa
Andrew Chen
author_sort Johnson Huang
collection DOAJ
description Purpose. To report a case of postoperative endophthalmitis after combined cataract extraction and iStent inject implantation. Observation. A 70-year-old male with a nuclear sclerotic cataract and primary open-angle glaucoma underwent an uneventful phacoemulsification cataract extraction with implantation of an intraocular lens and an iStent inject trabecular bypass stent. The patient was prescribed a postoperative regimen of ofloxacin 0.3% and prednisolone acetate 1%, 1 drop four times a day each. On postoperative day five, he presented to the emergency room for eye pain and had 4+ mixed cells in the anterior chamber (AC) without hypopyon or vitritis on exam. Prednisolone 1% eye drops were increased from four times a day to every two hours while awake. Overnight, he developed worsening vision and severe eye pain. The next morning, he was found to have increased AC cells, vitritis, and intraretinal hemorrhages and was diagnosed with endophthalmitis. The patient underwent a vitreous tap and intravitreal injections of vancomycin (1 mg/0.1 mL) and amikacin (0.4 mg/0.1 mL). Cultures grew Staphylococcus epidermidis. Lab work-up revealed underlying neutropenia. Visual acuity eventually recovered to 20/20. Conclusion and Importance. This report highlights a case of endophthalmitis associated with placement of the iStent inject. The infection was well-controlled after administration of intravitreal antibiotics without removal of the iStent inject, and visual acuity eventually recovered to 20/20. Surgeons should be aware of endophthalmitis risk following combined iStent inject placement, and good recovery is possible without removal of the implant.
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spelling doaj.art-7419bf6b33054fc59d1afa837b3dd8bf2023-05-12T00:00:02ZengHindawi LimitedCase Reports in Ophthalmological Medicine2090-67302023-01-01202310.1155/2023/3132866Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject ImplantationJohnson Huang0Minh T. Nguyen1Mai Tsukikawa2Andrew Chen3Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyPurpose. To report a case of postoperative endophthalmitis after combined cataract extraction and iStent inject implantation. Observation. A 70-year-old male with a nuclear sclerotic cataract and primary open-angle glaucoma underwent an uneventful phacoemulsification cataract extraction with implantation of an intraocular lens and an iStent inject trabecular bypass stent. The patient was prescribed a postoperative regimen of ofloxacin 0.3% and prednisolone acetate 1%, 1 drop four times a day each. On postoperative day five, he presented to the emergency room for eye pain and had 4+ mixed cells in the anterior chamber (AC) without hypopyon or vitritis on exam. Prednisolone 1% eye drops were increased from four times a day to every two hours while awake. Overnight, he developed worsening vision and severe eye pain. The next morning, he was found to have increased AC cells, vitritis, and intraretinal hemorrhages and was diagnosed with endophthalmitis. The patient underwent a vitreous tap and intravitreal injections of vancomycin (1 mg/0.1 mL) and amikacin (0.4 mg/0.1 mL). Cultures grew Staphylococcus epidermidis. Lab work-up revealed underlying neutropenia. Visual acuity eventually recovered to 20/20. Conclusion and Importance. This report highlights a case of endophthalmitis associated with placement of the iStent inject. The infection was well-controlled after administration of intravitreal antibiotics without removal of the iStent inject, and visual acuity eventually recovered to 20/20. Surgeons should be aware of endophthalmitis risk following combined iStent inject placement, and good recovery is possible without removal of the implant.http://dx.doi.org/10.1155/2023/3132866
spellingShingle Johnson Huang
Minh T. Nguyen
Mai Tsukikawa
Andrew Chen
Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
Case Reports in Ophthalmological Medicine
title Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
title_full Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
title_fullStr Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
title_full_unstemmed Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
title_short Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation
title_sort postoperative endophthalmitis after combined cataract extraction and istent inject implantation
url http://dx.doi.org/10.1155/2023/3132866
work_keys_str_mv AT johnsonhuang postoperativeendophthalmitisaftercombinedcataractextractionandistentinjectimplantation
AT minhtnguyen postoperativeendophthalmitisaftercombinedcataractextractionandistentinjectimplantation
AT maitsukikawa postoperativeendophthalmitisaftercombinedcataractextractionandistentinjectimplantation
AT andrewchen postoperativeendophthalmitisaftercombinedcataractextractionandistentinjectimplantation