Histamine and Histamine H4 Receptor Promotes Osteoclastogenesis in Rheumatoid Arthritis
Abstract Histamine H4 receptor (H4R) has immune-modulatory and chemotaxic effects in various immune cells. This study aimed to determine the osteoclastogenic role of H4R in rheumatoid arthritis (RA). The concentration of histamine in synovial fluid (SF) and sera in patients with RA was measured usin...
Main Authors: | Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee, Gary S. Firestein, Hae-Rim Kim |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-01101-y |
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