The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review
Background: Primary spinal osteosarcoma is a rare and intractable disease. Although en bloc resection is favorable for longer survival, it is not always achievable. Separation surgery, a partial resection with circumferential separation to safely deliver high-dose irradiation including intensity-mod...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-05-01
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| Series: | Clinical Medicine Insights: Case Reports |
| Online Access: | https://doi.org/10.1177/11795476231171891 |
| _version_ | 1797835168484950016 |
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| author | Yutaro Kanda Yuji Kakiuchi Takashi Yurube Yoshiki Takeoka Kunihiko Miyazaki Ryosuke Kuroda Kenichiro Kakutani |
| author_facet | Yutaro Kanda Yuji Kakiuchi Takashi Yurube Yoshiki Takeoka Kunihiko Miyazaki Ryosuke Kuroda Kenichiro Kakutani |
| author_sort | Yutaro Kanda |
| collection | DOAJ |
| description | Background: Primary spinal osteosarcoma is a rare and intractable disease. Although en bloc resection is favorable for longer survival, it is not always achievable. Separation surgery, a partial resection with circumferential separation to safely deliver high-dose irradiation including intensity-modulated radiation therapy (IMRT), has been recently indicated for patients with spinal cord compression secondary to solid tumor metastases. However, little evidence regarding this combination approach to spinal osteosarcoma exists. Case presentation: We report a 55-year-old male patient with a T1 tumor who underwent urgent decompression surgery for epidural spinal cord compression. Pathological findings revealed primary osteosarcoma. Separation surgery, IMRT, and adjuvant chemotherapy were applied to reduce the symptoms of epidural spinal cord compression. The patient was alive without local recurrence at the 5-year follow-up. Conclusions: Separation surgery with IMRT can be a relatively safe and effective treatment option in patients with osteosarcoma adjacent to spinal cord when en-bloc resection is challenging. |
| first_indexed | 2024-04-09T14:49:59Z |
| format | Article |
| id | doaj.art-741e98e936024e22878877f1512f4671 |
| institution | Directory Open Access Journal |
| issn | 1179-5476 |
| language | English |
| last_indexed | 2024-04-09T14:49:59Z |
| publishDate | 2023-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical Medicine Insights: Case Reports |
| spelling | doaj.art-741e98e936024e22878877f1512f46712023-05-02T09:46:13ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762023-05-011610.1177/11795476231171891The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature ReviewYutaro KandaYuji KakiuchiTakashi YurubeYoshiki TakeokaKunihiko MiyazakiRyosuke KurodaKenichiro KakutaniBackground: Primary spinal osteosarcoma is a rare and intractable disease. Although en bloc resection is favorable for longer survival, it is not always achievable. Separation surgery, a partial resection with circumferential separation to safely deliver high-dose irradiation including intensity-modulated radiation therapy (IMRT), has been recently indicated for patients with spinal cord compression secondary to solid tumor metastases. However, little evidence regarding this combination approach to spinal osteosarcoma exists. Case presentation: We report a 55-year-old male patient with a T1 tumor who underwent urgent decompression surgery for epidural spinal cord compression. Pathological findings revealed primary osteosarcoma. Separation surgery, IMRT, and adjuvant chemotherapy were applied to reduce the symptoms of epidural spinal cord compression. The patient was alive without local recurrence at the 5-year follow-up. Conclusions: Separation surgery with IMRT can be a relatively safe and effective treatment option in patients with osteosarcoma adjacent to spinal cord when en-bloc resection is challenging.https://doi.org/10.1177/11795476231171891 |
| spellingShingle | Yutaro Kanda Yuji Kakiuchi Takashi Yurube Yoshiki Takeoka Kunihiko Miyazaki Ryosuke Kuroda Kenichiro Kakutani The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review Clinical Medicine Insights: Case Reports |
| title | The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review |
| title_full | The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review |
| title_fullStr | The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review |
| title_full_unstemmed | The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review |
| title_short | The Combination of Separation Surgery and Intensity Modulated Radiation Therapy (IMRT) for a Primary Osteosarcoma of the Spine: A Case Report and Literature Review |
| title_sort | combination of separation surgery and intensity modulated radiation therapy imrt for a primary osteosarcoma of the spine a case report and literature review |
| url | https://doi.org/10.1177/11795476231171891 |
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