PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION

Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications,...

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Main Authors: N. A. Shostak, A. A. Klimenko, N. A. Demidova, I. V. Novikov
Format: Article
Language:English
Published: Столичная издательская компания 2016-01-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/750
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author N. A. Shostak
A. A. Klimenko
N. A. Demidova
I. V. Novikov
author_facet N. A. Shostak
A. A. Klimenko
N. A. Demidova
I. V. Novikov
author_sort N. A. Shostak
collection DOAJ
description Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented.
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spelling doaj.art-742081c33a9c4b3692950e06492be2802024-04-01T07:43:28ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-017219920310.20996/1819-6446-2011-7-2-199-203749PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSIONN. A. Shostak0A. A. Klimenko1N. A. Demidova2I. V. Novikov3Russian State Medical UniversityRussian State Medical UniversityRussian State Medical UniversityRussian State Medical UniversityData about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented.https://www.rpcardio.online/jour/article/view/750pulmonary hypertensionchronic thromboembolic pulmonary hypertensionthromboembolism of pulmonary arterythromboendarterectomybosentanprostacyclin analoguesphosphodiesterase-5 inhibitors
spellingShingle N. A. Shostak
A. A. Klimenko
N. A. Demidova
I. V. Novikov
PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
Рациональная фармакотерапия в кардиологии
pulmonary hypertension
chronic thromboembolic pulmonary hypertension
thromboembolism of pulmonary artery
thromboendarterectomy
bosentan
prostacyclin analogues
phosphodiesterase-5 inhibitors
title PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
title_full PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
title_fullStr PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
title_full_unstemmed PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
title_short PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
title_sort pathogenetic mechanisms and treatment principles of chronic thromboembolic pulmonary hypertension
topic pulmonary hypertension
chronic thromboembolic pulmonary hypertension
thromboembolism of pulmonary artery
thromboendarterectomy
bosentan
prostacyclin analogues
phosphodiesterase-5 inhibitors
url https://www.rpcardio.online/jour/article/view/750
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