PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION
Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications,...
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Format: | Article |
Language: | English |
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Столичная издательская компания
2016-01-01
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Series: | Рациональная фармакотерапия в кардиологии |
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Online Access: | https://www.rpcardio.online/jour/article/view/750 |
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author | N. A. Shostak A. A. Klimenko N. A. Demidova I. V. Novikov |
author_facet | N. A. Shostak A. A. Klimenko N. A. Demidova I. V. Novikov |
author_sort | N. A. Shostak |
collection | DOAJ |
description | Data about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented. |
first_indexed | 2024-03-08T14:04:04Z |
format | Article |
id | doaj.art-742081c33a9c4b3692950e06492be280 |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-04-24T15:59:21Z |
publishDate | 2016-01-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-742081c33a9c4b3692950e06492be2802024-04-01T07:43:28ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-017219920310.20996/1819-6446-2011-7-2-199-203749PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSIONN. A. Shostak0A. A. Klimenko1N. A. Demidova2I. V. Novikov3Russian State Medical UniversityRussian State Medical UniversityRussian State Medical UniversityRussian State Medical UniversityData about chronic thromboembolic pulmonary hypertension (CTPH) prevalence is presented. The main CTPH clinical manifestations are described. The possible reasons and pathogenetic mechanisms of CTPH development are discussed. Features of unfavorable disease prognosis are also presented. Indications, results, limitations for CTPH surgical treatment are shown. Data of the currently completed clinical studies on bosentan, prostacyclin analogues and phosphodiesterase-5 inhibitors usage in CTPH are presented.https://www.rpcardio.online/jour/article/view/750pulmonary hypertensionchronic thromboembolic pulmonary hypertensionthromboembolism of pulmonary arterythromboendarterectomybosentanprostacyclin analoguesphosphodiesterase-5 inhibitors |
spellingShingle | N. A. Shostak A. A. Klimenko N. A. Demidova I. V. Novikov PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION Рациональная фармакотерапия в кардиологии pulmonary hypertension chronic thromboembolic pulmonary hypertension thromboembolism of pulmonary artery thromboendarterectomy bosentan prostacyclin analogues phosphodiesterase-5 inhibitors |
title | PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION |
title_full | PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION |
title_fullStr | PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION |
title_full_unstemmed | PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION |
title_short | PATHOGENETIC MECHANISMS AND TREATMENT PRINCIPLES OF CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION |
title_sort | pathogenetic mechanisms and treatment principles of chronic thromboembolic pulmonary hypertension |
topic | pulmonary hypertension chronic thromboembolic pulmonary hypertension thromboembolism of pulmonary artery thromboendarterectomy bosentan prostacyclin analogues phosphodiesterase-5 inhibitors |
url | https://www.rpcardio.online/jour/article/view/750 |
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