Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease
Gastrointestinal lesions resulting from immunoglobulin G4-related disease are classified into two types: One is a gastrointestinal lesion showing marked thickening of the wall, and the other is an IgG4-related pseudotumor. We report the case of a woman with gastric calcifying fibrous tumor undergoin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | The Saudi Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=6;spage=423;epage=426;aulast=Zhang |
| _version_ | 1811332826701758464 |
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| author | Hejun Zhang Zhu Jin Shigang Ding |
| author_facet | Hejun Zhang Zhu Jin Shigang Ding |
| author_sort | Hejun Zhang |
| collection | DOAJ |
| description | Gastrointestinal lesions resulting from immunoglobulin G4-related disease are classified into two types: One is a gastrointestinal lesion showing marked thickening of the wall, and the other is an IgG4-related pseudotumor. We report the case of a woman with gastric calcifying fibrous tumor undergoing endoscopic resection that contained 62 IgG4+ plasma cells per high-power field and an IgG4-to-IgG ratio of 41% in lesional plasma cells, which shared clinical and histopathological features associated with gastric IgG4-related pseudotumor. So, we postulate that calcifying fibrous tumor as part of the spectrum of IgG4-related disease might be the unifying concept with IgG4-related pseudotumor. Meanwhile, the patient had coexistent autoimmune diseases, including autoimmune atrophic gastritis, Hashimoto's thyroiditis, and possible primary biliary cirrhosis. The clinical follow-up evaluation was uneventful. |
| first_indexed | 2024-04-13T16:42:55Z |
| format | Article |
| id | doaj.art-74216db1dfac4b1bb0fdc352a2d02c19 |
| institution | Directory Open Access Journal |
| issn | 1319-3767 1998-4049 |
| language | English |
| last_indexed | 2024-04-13T16:42:55Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Saudi Journal of Gastroenterology |
| spelling | doaj.art-74216db1dfac4b1bb0fdc352a2d02c192022-12-22T02:39:11ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492015-01-0121642342610.4103/1319-3767.170950Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric diseaseHejun ZhangZhu JinShigang DingGastrointestinal lesions resulting from immunoglobulin G4-related disease are classified into two types: One is a gastrointestinal lesion showing marked thickening of the wall, and the other is an IgG4-related pseudotumor. We report the case of a woman with gastric calcifying fibrous tumor undergoing endoscopic resection that contained 62 IgG4+ plasma cells per high-power field and an IgG4-to-IgG ratio of 41% in lesional plasma cells, which shared clinical and histopathological features associated with gastric IgG4-related pseudotumor. So, we postulate that calcifying fibrous tumor as part of the spectrum of IgG4-related disease might be the unifying concept with IgG4-related pseudotumor. Meanwhile, the patient had coexistent autoimmune diseases, including autoimmune atrophic gastritis, Hashimoto's thyroiditis, and possible primary biliary cirrhosis. The clinical follow-up evaluation was uneventful.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=6;spage=423;epage=426;aulast=ZhangCalcifying fibrous tumorIgG4-related diseaseIgG4-related pseudotumorstomach |
| spellingShingle | Hejun Zhang Zhu Jin Shigang Ding Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease The Saudi Journal of Gastroenterology Calcifying fibrous tumor IgG4-related disease IgG4-related pseudotumor stomach |
| title | Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease |
| title_full | Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease |
| title_fullStr | Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease |
| title_full_unstemmed | Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease |
| title_short | Gastric calcifying fibrous tumor: A case of suspected immunoglobulin G4-related gastric disease |
| title_sort | gastric calcifying fibrous tumor a case of suspected immunoglobulin g4 related gastric disease |
| topic | Calcifying fibrous tumor IgG4-related disease IgG4-related pseudotumor stomach |
| url | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2015;volume=21;issue=6;spage=423;epage=426;aulast=Zhang |
| work_keys_str_mv | AT hejunzhang gastriccalcifyingfibroustumoracaseofsuspectedimmunoglobuling4relatedgastricdisease AT zhujin gastriccalcifyingfibroustumoracaseofsuspectedimmunoglobuling4relatedgastricdisease AT shigangding gastriccalcifyingfibroustumoracaseofsuspectedimmunoglobuling4relatedgastricdisease |