Comparison of blood lead levels in children and adolescents with and without functional abdominal pain
Background: Functional abdominal pain is a health concern with chronic abdominal discomfort without clear etiology. Several etiologic factors are raised in this regard, one related to environmental factors. This study aimed to compare blood lead levels between children and adolescents with and witho...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Advanced Biomedical Research |
| Subjects: | |
| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=194;epage=194;aulast=Famouri |
| _version_ | 1797649505598832640 |
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| author | Fatemeh Famouri Maryam Yazdi Awat Feizii Hossein Saneian Peiman Nasri Roya Kelishadi |
| author_facet | Fatemeh Famouri Maryam Yazdi Awat Feizii Hossein Saneian Peiman Nasri Roya Kelishadi |
| author_sort | Fatemeh Famouri |
| collection | DOAJ |
| description | Background: Functional abdominal pain is a health concern with chronic abdominal discomfort without clear etiology. Several etiologic factors are raised in this regard, one related to environmental factors. This study aimed to compare blood lead levels between children and adolescents with and without functional abdominal pain.
Materials and Methods: This case–control study was performed in 2019–2020 in Isfahan, Iran. The sample size was calculated as 70 cases and an equal number of controls. Cases were children and adolescents with functional gastrointestinal disorder (FGID), and controls were grouped age- and sex-matched. Controls were randomly selected from those referred for routine health screening. Both groups obtained blood lead, iron, and calcium levels. All participants completed the FFQ Food Consumption and Environmental Pollutants Questionnaire.
Results: Participants were 139 children (68 cases and 71 controls). The mean (SD) age was 9.40 (3.91) years in the FGID group and 8.79 (3.46) years in the controls (P = 0.330). The mean (SD) blood lead level was not significantly different between the FGID group and the controls (3.98 ± 2.56 vs 3.81 ± 1.96 μg/dl, respectively, P = 0.670). We found that 55.3% of children with high lead levels had FGID, while 44.4% of children with lower lead levels had FGID, but the difference was not statistically significant (P = 0.33).
Conclusion: We found that the lead level was higher in patients with FGID than in the controls; however, this difference was not significantly different. This might be because of elevated lead levels in both groups. Future ecological studies with a large sample size are necessary in this regard. |
| first_indexed | 2024-03-11T15:48:05Z |
| format | Article |
| id | doaj.art-74251c55087e488095d31beecd600914 |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-03-11T15:48:05Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-74251c55087e488095d31beecd6009142023-10-26T05:43:17ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752023-01-0112119419410.4103/abr.abr_250_22Comparison of blood lead levels in children and adolescents with and without functional abdominal painFatemeh FamouriMaryam YazdiAwat FeiziiHossein SaneianPeiman NasriRoya KelishadiBackground: Functional abdominal pain is a health concern with chronic abdominal discomfort without clear etiology. Several etiologic factors are raised in this regard, one related to environmental factors. This study aimed to compare blood lead levels between children and adolescents with and without functional abdominal pain. Materials and Methods: This case–control study was performed in 2019–2020 in Isfahan, Iran. The sample size was calculated as 70 cases and an equal number of controls. Cases were children and adolescents with functional gastrointestinal disorder (FGID), and controls were grouped age- and sex-matched. Controls were randomly selected from those referred for routine health screening. Both groups obtained blood lead, iron, and calcium levels. All participants completed the FFQ Food Consumption and Environmental Pollutants Questionnaire. Results: Participants were 139 children (68 cases and 71 controls). The mean (SD) age was 9.40 (3.91) years in the FGID group and 8.79 (3.46) years in the controls (P = 0.330). The mean (SD) blood lead level was not significantly different between the FGID group and the controls (3.98 ± 2.56 vs 3.81 ± 1.96 μg/dl, respectively, P = 0.670). We found that 55.3% of children with high lead levels had FGID, while 44.4% of children with lower lead levels had FGID, but the difference was not statistically significant (P = 0.33). Conclusion: We found that the lead level was higher in patients with FGID than in the controls; however, this difference was not significantly different. This might be because of elevated lead levels in both groups. Future ecological studies with a large sample size are necessary in this regard.http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=194;epage=194;aulast=Famouriabdominal painchildfunctionallead |
| spellingShingle | Fatemeh Famouri Maryam Yazdi Awat Feizii Hossein Saneian Peiman Nasri Roya Kelishadi Comparison of blood lead levels in children and adolescents with and without functional abdominal pain Advanced Biomedical Research abdominal pain child functional lead |
| title | Comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| title_full | Comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| title_fullStr | Comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| title_full_unstemmed | Comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| title_short | Comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| title_sort | comparison of blood lead levels in children and adolescents with and without functional abdominal pain |
| topic | abdominal pain child functional lead |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=194;epage=194;aulast=Famouri |
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